:Comparison of Clinical Effects between Adults and Children

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We evaluated the therapeutic effect of leftose in 30 adults and children with chronic paranasal sinusitis or chronic rhinitis.1) Marked improvement was seen in 5 cases (17%), moderate improvement in 9 (30%), slight improvement in 5 (17%), and no effect in 11 (37%).2) Objective improvement was observed in the following signs and examination results: Nasal obstruction improved in 66.7% of the adults and 60.0% of the children, rhinorrhea in 64.3% and 73.3%, X-ray findings in 25.0% and 57.1%, and smears in 46.2% and 60.0%.3) The drug was more effective in children than in adults.4) In adults subjective symptoms correlated well with smears, while in children they correlated with both X-ray films and smears.5) If the evaluation of adults had included smears and subjective symptoms, the number of the improved cases might have been higher.6) No adverse effect was observed in any of the patients.
耳鼻咽喉科臨床学会の論文