めまい・平衡障害例におけるセロクラ-ル(酒石酸イフェンプロジル)の使用経験--末梢性障害例における検討

概要

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The effects of Cerocral (Ifenprodil tartrate) were clinically studied in 22 patients with peripheral vertigo and dysequilibrium. These effects were assessed by subjective and objective parameters. A "vertigo diary" was used for subjective evaluation.The following results were obtained.1) As to the subjective parameters, Cerocral was effective on "vertigo" (84.2%), "heavy feeling of the head" or "headache" (68.8%) and "nausea and/or vomiting" (60.0%). On the other hand, the effects on "shoulder stiffness", "sleeplessness" and "feelings of lassitude" were limited, and on "tinnitus" and "hearing impairment" were nonexistent.2) As to the objective parameters, Cerocral was effective for the "nystagmus test" (88.9%), but not for the "hearing test" (6.7%).3) Side effects were observed in three patients, but these were not very severe.4) In light of these results, Cerocral appears to be effective for the treatment of peripheral vertigo and dysequilibrium, and safely usable.
耳鼻咽喉科臨床学会の論文