Treatment of Perceptive Deafness with Combination of K and Mg L-aspartate and Vitamin B1

概要

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A combination therapy of potassium and magnesium salts of L-aspartic acid (ASPARA) and vitamin B1 derivative (BESTON) was given to patients with the chiefcomplaints of tinnitus and hearing impairment, including 11 patients caused by streptomycin therapy, and to 9 patients due to other causes.As results, the following effects were observed.Of 11 patients (22 ears) due to streptomycin therapy, 1 patient (2 ears) responded to the combination therapy remarkably and 3 patients (4 ears) satisfactorily. 3 patients (4 ears) and 7 patients (8 ears) responded to the therapy remarkably and satisfactorily, those due to other causes (e. g. sound injury, poisoning). Patients with low tone hearing impairment were treated more effectively than those to high tone. It is desirous to start any treatment of the diseases at anearlier stage of onset of symptoms. This therapy was proved to show a sure effect when administered within a week after onset of the symptoms. With regard to the patient of hearing impairment due to streptomycin, serum level of Na, K, Cl and Ca, liver and renal function before administration of the therapy were recorded. From examination of these data, there was no correlation between the total amount of streptomycin and development of hearing impairment or the effect of the combination therapy.
耳鼻咽喉科臨床学会の論文