内耳蝸牛内基底板上に生じる進行波の動的挙動計測

概要

論文の詳細を見る
It is said that characteristic frequency distribution of a cochlea is quite wide and a cochlear basilar membrane (BM) plays an important role in its frequency selectivity. It is also known that a traveling wave propagates along the BM from base to apex. Recently, it has been reported that outer hair cell motility amplifies the BM vibrations. However, the dynamic behavior of the traveling wave propagated from base to apex on the BM is obscure. Therefore, in this study, first, the glass microbeads are dispensed into the cochlea from a small hole which is opened at the scala tympani of the basal turn and fell onto the BM, and the BM vibrations in live and dead guinea pigs are measured directly using a laser Doppler velocimeter coupled to a compound microscope. Then, an attempt is made to clarify the dynamic behavior of the traveling wave. Results indicate that the traveling wave velocity depends on the BM vibrations amplitude and that the traveling wave velocity when the BM vibrations amplitude is large is smaller than that when its amplitude is small.
社団法人日本機械学会の論文
1999-08-25