A case report of Plunmmer-Vinson syndrome with abnormality of taste.

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This paper described a case of Plummer-Vinson syndrome and developmental changes of 4 primary taste qualities; sweet, sour, bitter and salty.<BR>In the patient, a male aged 78, a typical iron-deficiency anemia state was comfirmed by routine hematology. The tongue was very smooth because of atrophy of the filiform papillae and he had spoon-shaped nails. Slight difficulty of swallowing was also complained. Taste threshold values and difference threshold values of 4 taste qualities increased with this patient, especially sweet, sour and salty. Bitter was the only taste usually recognized.<BR>Following treatment with iron derivatives, there was much improvement and abnormal findings almost disappeared. The taste threshold values and difference threshold values for 4 taste qualities gradually decreased with improvement of iron-deficiency anemia. Therefore the taste abnormality of this patient was caused by atrophy of the papillae of tongue from irondeficiency anemia.