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184 HBs antigen positive patients aged over 65 years old on the basis of informations obtained by questionnaire methord from 19 National Hospitals were studied. Out of 184 patients, 99 were male and 85 female. 92 cases asymptomatic HBV carrier (ASC), 59 chronic liver disease, 27 hepatoma and 6 others. HBe-Ag positive was in 10 out of 23 patients with ASC (28.6%), in 5 out of 23 patients with chronic liver disease (21.6%), and in 4 of 6 patients with hepatoma (66.7%). Twelve patients died of cirrhosis, and 22 patients died of hepatoma. Cirrhosis was found in all of the patients with hepatoma. As a characteristic of HBs-Ag positive old aged patients, nearly half of the patients were ASC; the liver disease is thought to be occured ever from the HBV carrier over 60 years old. Patients with HBe-Ag positive also had a high percentage of developing hepatoma as a complication.
財団法人日本消化器病学会の論文