A Physico-Chemical Study of the DNA-Binding Domain of GATA1.
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概要
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The structure and DNA-binding characteristics of the two zinc-binding units of GATA-1 were studied by using synthetic peptides. We show that both units bind to Zn2+ and Co2+ but neither of them to Fe2+, and that both units interact with DNA. Some results shown in this paper can be explained by dimerisation of the units.
- 日本学士院の論文
著者
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SUZUKI Masashi
MRC Lab. of Mol. Biol.
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Aimoto Saburo
Institude For Protein Research Osaka University
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JOHNSON Tony
MRC Laboratory of Molecular Biology
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CHOTHIA Lucy
MRC Laboratory of Molecular Biology
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