DNA Recognition Rules for Steroid Hormone Receptors and GATA1 (1): Chemical and Stereochemical Rules.
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DNA recognition rules for transcription factors of class C4 are discussed in the light of three dimensional structures determined by crystallography or NMR. The rules have two parts; the chemical rules which list possible amino acid side-chains and DNA bases partners, and the Stereochemical rules which describe how the positions of the residues and bases which make contact are determined by the orientation and packing of the α-helix in the major groove of DNA.
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関連論文
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