Three adult cases accomplished HBV carrier state after sporadic infection of acute B-type hepatitis.

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An accomplishment of HBV carrier state has been thought to be due to HBV infection passing from a mother to the fetus or neonate, infection in childhood and in adult accompanied with immune disturbance state. Thus the condition in the healthy adult is thought to be very rare. We described 3 cases of adult accomplished HBV carrier state after sporadic infection of Btype hepatitis. All of these cases were confirmed that serum anti-HBc was negative in the early stage of the heatitis and, thereafter, showed a higher level of anti-HBc. Serum HBs antigen and HBe antigen were continued positive and high level in HBV-DNA-polymerase activity for more than 1 year after the occurence of hepatitis. These cases were non-icteric and the symptoms of the hepatitis were relatively slight.
社団法人日本肝臓学会の論文