医療従事者におけるB型肝炎ウイルス感染の疫学的研究

概要

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To clarify the epidemiologic features of occupationally acquired hepatitis B virus (HBV) infection among medical personnel, the authors carried out a seroepidemiologic survey of the 1642 employees in the Nihon University Hospital. The frequency of the HBs antigen in the personnel and blood donors was not differ significantly. However, the HBs antibody frequency was highest in surgeons (20.9%), obsterics-gynecologist (20.4%), ophthalmologist (22.2%), nurses (17.4%) and radiologic technicians (18.4%) in comparison to the controls (10.4%) and those in the practices of Internal medicine (7.5%) and pediatrics (5.9%). Thus, it would appeal. that exposure to blood and blood products rather than patient contact without such exposure might be the important risk factor for HBV infection. Although the prevalence of the HBs antibody in hospital personnel rose at a significantly higher rate with advancing age than did such prevalence among the comparison group, there was an accelerated phase of rising HBs antibody prevalence during the early years of clinical practice and training for hospital employees, after which the rate of increase appeared to plateau. Our results suggest that HBV infection constitutes a significant occupational risk for medical personnel.
社団法人日本肝臓学会の論文