A case of rheumatoid arthritis complicated with systemic lupus erythematosus and Sjögren's syndrome

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In this report, we described a patient of overlap syndrome of rheumatoid arthritis (RA) with sjögren's syndrome and systemic lupus erythematosus (SLE).She had been treated for definite RA for ten years until she was made a diagnosis of SLE according to an oral ulcer, pleuritis, hemolytic anemia, lymphocytopenia, positive reaction of LE test, and existence of various anto-antibodies.Also she was suggested to be accompanied with sjögren's syndrome by dry mouth, dry eye, and keratoconjunctivitis sicca.After the treatment with prednisolone, marked improvement of clinical features and laboratorial data were observed.Up to the present, the case report of overlap syndrome of RA and SLE is rare. This case has many suggestive data about classification of collagen diseases.
日本臨床免疫学会の論文