SOME CHEMICAL AND PHARMACOLOGICAL PROPERTIES OF AN AMINE (MALTOXIN) ISOLATED FROM MALT ROOTLET
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概要
- 論文の詳細を見る
In the previous paper (1), it was reported that HCl-ethanol extract obtained from wheat gluten malt rootlet exhibited potent toxicity against mouse. In connection to the finding, further experiments have been carried out employing brew malt rootlet as a test material. As it has been known, the rootlet contains various amines, such as hordenine, choline, betaine, tyramine and N-methyltyramine, some of which exert certain pharmacological activities (2-10). During the course of our present studies, another amine was found in the HCl-ethanol extract of the brew malt rootlet. Differing from other amines noted, the amine, named "maltoxin, " was revealed to exhibit a strong contractile activity on the rectus muscle of frog. In this paper the method of preparation and some of the chemical and pharmacological properties of this active principle are described.
- 公益社団法人 日本薬理学会の論文
著者
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Hayama Toyoaki
Laboratory Of Veterinary Pharmacology Faculty Of Agriculture Tokyo University Of Agriculture And Tec
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URAKAWA Norimoto
Department of Veterinaly Pharmacology, Faculty of Agriculture, University of Tokyo
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DEGUCHI TAKEHIKO
Department of Veterinary Pharmacology, Faculty of Agriculture, University of Tokyo
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OHKUBO YOSHIO
Department of Veterinary Pharmacology, Faculty of Agriculture, University of Tokyo
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HAYAMA TOYOAKI
Laboratory of Pharmacology and Toxicology, Institute of Food Microbiology, University of Chiba
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