DECAMETHONIUM-LIKE ACTION OF MALTOXIN, AN ACTIVE PRINCIPLE FROM MALT ROOTLET, ON THE FROG MUSCLE
スポンサーリンク
概要
- 論文の詳細を見る
In the preceding papers (1, 2), maltoxin, a basic substance isolated from malt rootlet, was reported to cause peripheral paralysis in the frog, and this effect was attributed to the blockade of neuromuscular transmission which differs from that due to <I>d</I>-tubocurarine, because of a stimulant effect on the rectus muscle of the frog.<BR> In the present experiments the mode of neuromuscular block produced by maltoxin was further studied in the muscle. It was suggested that maltoxin has a dual mode of blocking action resembling that seen in decamethonium. That is, it depolarizes the frog muscle and at the same time decreases the sensitivity of the muscle to acetylcholine.<BR> The neuromuscular block by decamethonium was also examined for comparison.
- 公益社団法人 日本薬理学会の論文
著者
-
URAKAWA Norimoto
Department of Veterinaly Pharmacology, Faculty of Agriculture, University of Tokyo
-
DEGUCHI TAKEHIKO
Department of Veterinary Pharmacology, Faculty of Agriculture, University of Tokyo
-
OHKUBO YOSHIO
Department of Veterinary Pharmacology, Faculty of Agriculture, University of Tokyo
関連論文
- HYPEROSMOTIC APPLICATIONS OF KCI INDUCE VASCULAR SMOOTH MUSCLE CONTRACTION WHICH IS INDEPENDENT OF EXTERNAL Ca
- THE INHIBITORY EFFECT OF PAPAVERINE ON RESPIRATION-DEPENDENT CONTRACTURE OF GUINEA PIG TAENIA COLI IN HIGH-K MEDIUM. II. INHIBITION OF MITOCHONDRIAL RESPIRATION
- THE INHIBITORY EFFECT OF PAPAVERINE ON RESPIRATION-DEPENDENT CONTRACTURE OF GUINEA PIG TAENIA COLI IN HIGH-K MEDIUM. I. THE RELATIONSHIP BETWEEN CONTRACTURE AND RESPIRATION
- THE INHIBITORY EFFECT OF PAPAVERINE ON RESPIRATION-DEPENDENT CONTRACTURE OF GUINEA PIG TAENIA COLI IN HIGH-K MEDIUM. III. THE DIFFERENTIAL EFFECT OF PAPAVERINE AND ROTENONE ON DT DIAPHORASE
- THE REGULATION OF RESPIRATION OF GUINEA PIG TAENIA COLT IN HIGH-K MEDIUM; THE ROLE OF NICOTINAMIDE-ADENINE DINUCLEOTIDE, ADENOSINE DIPHOSPHATE AND Ca++
- ARTIFICIAL BUFFERS DO NOT INHIBIT CONTRACTILE RESPONSES IN THE SMOOTH MUSCLE OF RAT PORTAL VEIN AND GUINEA PIG TAENIA COLI
- CHANGES IN TISSUE WEIGHT AND CALCIUM CONTENT IN VARIOUS HIGH POTASSIUM SOLUTIONS IN SMOOTH MUSCLE OF GUINEA PIG TAENIA COLI
- EFFECTS OF PALYTOXIN ON MECHANICAL AND ELECTRICAL ACTIVITIES OF GUINEA PIG PAPILLARY MUSCLE
- EFFECTS OF PALYTOXIN ON ISOLATED INTESTINAL AND VASCULAR SMOOTH MUSCLES
- ON THE INHIBITORY MECHANISM OF BASSIANOLIDE, A CYCLODEPSIPEPTIDE, IN ACETYLCHOLINE-INDUCED CONTRACTION IN GUINEA-PIG TAENIA COLI
- INHIBITORY EFFECT OF BASSIANOLIDE, A CYCLODEPSIPEPTIDE, ON DRUG-INDUCED CONTRACTIONS OF ISOLATED SMOOTH MUSCLE PREPARATIONS
- INHIBITORY EFFECTS OF CAFFEINE ON DEVELOPED TENSION AND CALCIUM MOVEMENT IN GUINEA PIG TAENIA COLI IN HIGH-K MEDIUM
- VERAPAMIL-INDUCED TRANSMITTER RELEASE IN RAT DIAPHRAGM MUSCLE
- EFFECTS OF OUABAIN ON HIGH-K INDUCED CONTRACTIONS OF VARIOUS SMOOTH MUSCLE TISSUES IN THE GUINEA-PIG
- EFFECTS OF Li-SUBSTITUTION ON HIGH-K INDUCED ONTRACTIONS OF VARIOUS SMOOTH MUSCLE TISSUES IN THE GUINEA-PIG
- INFLUENCE OF DIDS ON THE DUAL ACTIONS OF VANADATE ON HIGH K-INDUCED CONTRACTION IN THE GUINEA-PIG TAENIA COLI
- DUAL ACTIONS OF VANADATE ON HIGH K-INDUCED CONTRACTION IN GUINEA-PIG TAENIA COLI
- POTENTIATION OF INDIRECTLY INDUCED MUSCLE TWITCHES BY ORGANIC CALCIUM ANTAGONISTS IN PHRENIC NERVE-DIAPHRAGM MUSCLE PREPARATIONS OF MICE
- EFFECTS OF VERAPAMIL ON TWITCH POTENTIATION INDUCED BY INDIRECT CONDITIONING STIMULATION IN MOUSE PHRENIC NERVE-DIAPHRAGM MUSCLE PREPARATION
- A TRANSPORT MECHANISM OF MERCURY INTO OVARIAN FOLLICLES IN LAYING QUAIL
- Inhibitory Effect of Beauvericin on a High K+-Induced Tonic Contraction in Guinea-Pig Taenia Coli
- THE MECHANISM OF CONTRACTILE ACTION OF PALYTOXIN ON VASCULAR SMOOTH MUSCLE OF GUINEA-PIG AORTA
- EFFECT OF HISTAMINE ON CALCIUM MOVEMENT IN GUINEA PIG TAENIA COLI
- EFFECT OF CAFFEINE ON CONTRACTILE ACTIVITY AND CALCIUM MOVEMENT IN GUINEA PIG TAENIA COLI
- EFFECT OF CHOLINERGIC DRUGS AND BARIUM ON OXYGEN CONSUMPTION IN GUINEA PIG TAENIA COLI
- EFFECT OF HISTAMINE ON OXYGEN CONSUMPTION IN GUINEA PIG TAENIA COLI
- EFFECT OF CHOLINERGIC DRUGS ON CALCIUM MOVEMENT IN GUINEA PIG TAENIA COLI
- EFFECT OF ESTROGENIZATION ON THE DISTRIBUTION OF RADIOMERCURY IN QUAIL
- ISOMETRIC AND ISOTONIC SPONTANEOUS CONTRACTIONS OF GUINEA-PIG TAENIA COLI
- A SHIFT OF CELLULAR CALCIUM TO A MORE SLOWLY EXCHANGEABLE FRACTION DURING CONTRACTION IN GUINEA PIG TAENIA COLI
- High K+,Na+-deficient solution inhibits tension,O2 consumption,and ATP synthesis in smooth muscle.
- INCREASE IN 85Sr UPTAKE BY ELEVATED CONCENTRATION OF K IN GUINEA PIG TAENIA COLI
- COMPARISON BETWEEN ISOMETRIC AND ISOTONIC CONTRACTIONS IN GUINEA-PIG TAENIA COLI UNDER ANOXIA
- Study on the contraction and oxygen consumption induced by high K,Na-deficient solution in the urinary bladder and gall bladder of guinea-pig.
- A change in inhibitory mechanism of Na+ deficiency on high K+-induced contraction in rat uterus with the progress of pregnancy.
- DECAMETHONIUM-LIKE ACTION OF MALTOXIN, AN ACTIVE PRINCIPLE FROM MALT ROOTLET, ON THE FROG MUSCLE
- Potassium-induced contraction in smooth muscle.
- SOME CHEMICAL AND PHARMACOLOGICAL PROPERTIES OF AN AMINE (MALTOXIN) ISOLATED FROM MALT ROOTLET
- THE PARALYZING ACTION OF MALTOXIN, AN ACTIVE PRINCIPLE FROM MALT ROOTLET, ON THE FROG MUSCLE
- Role of endothelium in the contractions induced by norepinephrine and clonidine in rat aorta.
- Increase in membrane permeability in the absence of Ca and Mg in the smooth muscle of guinea-pig taenia coli.
- Contractile effects of jellyfish toxin extracted from Carybdea rastonii on isolated rabbit aorta.
- Effects of palytoxin on Na, K and ATP contents of vascular smooth muscle of rabbit aorta.
- A comparative study of the contraction induced by high K/Na deficient solution in the trachea, gall bladder and urinary bladder in guinea-pig.
- Decrease in Muscle Tension and Reduced Pyridine Nucleotides of the Guinea Pig Ileal Longitudinal Smooth Muscle in High K+,Na+-Deficient Solution.
- The effect of trifluoperazine on muscle tension and cytoplasmic Ca2+ level in guinea pig ileum.
- Species differences in inhibitory effect of Li+ on high K+-induced contraction in the lleal longitudinal smooth muscle.
- Species differences in the inhibitory effect of ouabain on high K- induced contraction in the ileal longitudinal muscle.
- High K-induced contractions in rabbit and monkey tracheal smooth muscle.
- AN AUTORADIOGRAPHIC STUDY ON THE DISTRIBUTION OF MERCURY AND ITS TRANSFER TO THE EGG IN THE LAYING QUAIL