Effects of .ALPHA.-fluoromethylhistidine on increase in histidine decarboxylase activity of maternal mouse kidney observed during late pregnancy and evidence for its non-mast cell origin by using estrogen and W/WV mice.
スポンサーリンク
概要
- 論文の詳細を見る
The increase of histidine decarboxylase (HDC) activity during late pregnancy in the whole bodies of fetal mice and the kidneys of their mothers were almost completely inhibited by i.p. administration of 25 mg/kg of α-fluoromethylhistidine (α-FMH), a suicide inhibitor of HDC, starting on day 13 of pregnancy. The increase of HDC in fetal mice was previously shown to be in mast cells [T. Watanabe et al., Proc. Natl. Acad. Sci. U.S.A. 78, 4209-4212 (1981)]. The increase of HDC in maternal kidneys was examined by using estrogen and <I>W/W<SUP>V</SUP></I> mice, which were devoid of mast cells and infertile. Treatment of castrated mice with 17-β-estradiol increased the HDC activity of the kidney, and this increase was antagonized by concomitant treatment with clomiphene, an antiestrogen, confirming that the increase is mediated through an estrogen receptor. HDC activity in the kidney of <I>W/W<SUP>V</SUP></I> mice was also increased by estradiol treatment, indicating that HDC activity was associated with non-mast cells.
- 公益社団法人 日本薬理学会の論文
著者
-
Ohno Akira
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
-
Taguchi Yoshitaka
Department Of Pharmacology Ii Osaka University School Of Medicine Osaka
-
Maeyama Kazutaka
Department Of Pharmacology Ehime University School Of Medicine
-
Wada Hiroshi
Department Of Bioengineering And Robotics Tohoku University
-
Watanabe Takehiko
Department Of Mechanical Engineering Niigata University
-
MAEYAMA Kazutaka
Department of Pharmacology II, Osaka University School of Medicine
-
OHNO Akira
Department of Pharmacology II, Osaka University School of Medicine
関連論文
- A case of hepatocellular carcinoma with multiple lung, spleen, and remnant liver metastasis successfully treated by combination chemotherapy with the novel oral DPD-inhibiting chemotherapeutic drug S-1 and interferon-α
- Organic Field-effect Transistors Based on Solution-processible Dibenzotetrathiafulvalene Derivatives
- (Tetrathiafulvalene)(tetracyanoquinodimethane) as a Contact Material for n-Channel and Ambipolar Organic Transistors
- Syntheses and Properties of Oligothiophenes with Cyano and Hexyl Groups
- Cardiomyocytes Fuse with Surrounding Non-Cardiomyocytes and Re-enter the Cell Cycle(The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-197 Adult Cardiac Sca-1 Positive Cells Differentiate into Beating Cardiomyocytes(Development and Differentiation 1 (M) : PE34)(Poster Session (English))
- OE-359 Calcium/Calmodulin and Calcineurin Signaling is Involved in Cell Fusion between Adult Stem Cells and Cardiomyocytes(Development and Differentiation 2 (H) : OE45)(Oral Presentation (English))
- OE-105 Granulocyte-colony stimulating factor prevents transition from left ventricular hypertrophy to diastolic heart failure in hypertensive rats(Heart Failure, Basic 1 (M) : OE13)(Oral Presentation (English))
- Rat Neonatal Cardiomyocytes Fuse with Mammalian Somatic Cellsand Reenter Cell Cycle
- Mechanical Stress and Calcium Signaling Involve Trans-Differentiation of Skeletal Muscle Derived Cells
- PE-602 Homing and Differentiation of Intravenously Transplanted Cardiac Side Population Cells in Injured Myocardium(Molecular biology, myocardium-2 (M) PE106,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulati
- PE-564 Trichostatin A Induces Differentiation of Cardiac Side Population Cells into Beating Cardiomyocytes(Development and differentiation-3 (M) PE97,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Socie
- PE-533 Distinct Distribution of Cardiac Sca-1 Positive Cells in Normal and Ischemic Hearts(Regeneration (angionenesis/myocardial regeneration)-4 (M) PE90,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation S
- PE-107 Pluripotency of Clonal Expanded Sca-1 Expressing Cells Derived from the Adult Murine Heart(Development and differentiation-2 (M) PE18,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 3 Cardiac Sca-1+ and Side Population Cells in Cardiac Regeneration(Cardiac Regeneration,AHA-JCS Joint Symposium (M),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Dominance of Cardiac Phenotypes in the Fused Cells between Cardiomyocytes and Mature Somatic Cells in vivo(Development and Differentiation 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Cardiac SP Cells Differentiate into Beating Cardiac Myocytes in vitro(Development and Differentiation 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OE-360 Cardiomyocytes Fuse with Somatic Cells in Injured Heart(Development and Differentiation 2 (H) : OE45)(Oral Presentation (English))
- OE-207 Granulocyte-Colony Stimulating Factor Stimulates Preexisting Endothelial Cells and Promotes Blood Vessel Formation in vitro(Angiogenesis 1 (M) : OE26)(Oral Presentation (English))
- Convergence and Divergence, a Concept for Explaining Drug Actions
- Magnetic Properties in the Normal State of LuNi_2B_2C Observed by^Ni and ^B NMR
- INTERACTION OF THE INNER EAR MOTOR PROTEIN PRESTIN WITH CHLORIDE STUDIED BY ISOTHERMAL TITRATION CALORIMETRY(2A1 Micro & Nano Biomechanics IV)
- MISFOLDING AND MISLOCALIZATION BY MUTATIONS OF THE MOTOR PROTEIN PRESTIN(2A1 Micro & Nano Biomechanics IV)
- Effects of Mutation in the Conserved GTSRH Sequence of the Motor Protein Prestin on Its Characteristics(Bioengineering)
- Relationship between Fluorescence Intensity of GFP and the Expression Level of Prestin in a Prestin-Expressing Chinese Hamster Ovary Cell Line(Bioengineering)
- Stable Expression of the Motor Protein Prestin in Chinese Hamster Ovary Cells(Bioengineering)
- Antibacterial activity and PK/PD of ceftriaxone against penicillin-resistant Streptococcus pneumoniae and β-lactamase-negative ampicillin-resistant Haemophilus influenzae isolates from patients with community-acquired pneumonia
- Identification of VanB-Type Vancomycin Resistance in Entercoccus gallinarum from Japan
- HEAT-STRESS ACTUATED MECHANISM OF THE INNER EAR PROTECTING IT FROM TRAUMATIC NOISE EXPOSURE(2A1 Micro & Nano Biomechanics IV)
- A study of bone mineral density and physical growth in very low birth-weight infants after their discharge from hospital
- Experimental Assessment of the Performance of an Electromagnetic Hearing Aid in Human Temporal Bones(Bioengineering)
- Effects of Individual Differences in Size and Mobility of the Middle Ear on Hearing(Bioengineering)
- High-Speed Video Observation of Tympanic Membrane Rupture in Guinea Pigs(Bioengineering)
- PJ-471 Polyol Pathway Activation is More Contributed to Impaired Shear Stress-induced Endothelial Nitric Oxide Production in Hyperglycemia Than Oxidative Stress(Diabetes/Obesity/Metabolic syndrome(11)(H),Poster Session(Japanese),The 72nd Annual Scientific
- PJ-690 Determinants of In-hospital Death and Rupture in Stanford B Aortic Dissections(Peripheral circulation/Vascular disease-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Intravenous Myocardial Contrast Echocardiography and Multi-Detector Computed Tomography Predict Recovery of Regional Wall Motion in Reperfused Acute Myocardial Infarction
- Rupture of the Anterolateral Papillary Muscle Caused by a Single Diagonal Branch Obstruction
- Successful treatment of multiple hepatocellular carcinoma with tumor thrombi in the major portal branches by intraarterial 5-fluorouracil perfusion chemotherapy combined with subcutaneous interferon-alpha and hepatectomy
- Vitamin K2 has growth inhibition effect against hepatocellular carcinoma cell lines but does not enhance anti-tumor effect of combination treatment of interferon-α and fluorouracil in vitro
- Association Between Recurrence of Hepatocellular Carcinoma and α-Fetoprotein Messenger RNA Levels in Peripheral Blood
- Interferon alpha receptors are important for antiproliferative effect of interferon-α against human hepatocellular carcinoma cells
- Isolated metastasis to the gallbladder from hepatocellular carcinoma
- Identification of Multiple Regulatory Elements of Human L-Histidine Decarboxylase Gene
- Effect of Depth of Conical-Shaped Tympanic Membrane on Middle-Ear Sound Transmission
- Measurement of Dynamic Frequency Characteristics of Guinea Pig Middle Ear by a Laser Doppler Velocimeter
- Analysis of Second-order Kernel Response Components of Multifocal Electroretinograms Elicited from Normal Subjects
- Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats
- Atomic Force Microscopic Imaging of the Lateral Wall of the Guinea Pig Outer Hair Cell(Micro- and Nano-biomechanics)
- Phylogenetic Position of Acoel Turbellarians Inferred from Partial 18S rDNA Sequences
- THE PHARMACOLOGICAL ACTION OF PUROTHIONIN (The 6th Meeting for the Study of Toxic Effect)
- Successful outcome after resection of liver metastasis arising from an extraadrenal retroperitoneal paraganglioma that appeared 9 years after surgical excision of the primary lesion
- Structural Analysis of N-Glycans of Storage Glycoproteins in Soybean (Glycine max. L) Seed
- Structural Elucidation of N-Linked Sugar Chains of Storage Glycoproteins in Mature Pea (Pisum sativum) Seeds by Ion-spray Tandem Mass Spectrometry (IS-MS/MS)
- Detection of Histidine Decarboxylase (HDC) in Paraffin Sections of Formalin Fixed Rat Stomach Using Avidin-biotin-peroxidase-complex Method
- DISTRIBUTION OF THE HISTAMINERGIC NEURON SYSTEM AND ITS PHYSIOLOGICAL FUNCTION IN RAT BRAIN
- Analysis of trap distribution using time-of-flight spectroscopy
- Extraction of Trap Distribution in Organic Semiconductors by Transient Photocurrent
- Analysis of the Dynamic Behavior of the Inner Hair Cell Stereocilia by the Finite Element Method
- The Effect of Haloperidol on the Histaminergic Neuron System in the Rat Brain
- Active Force Generated by the Motility of the Outer Hair Cell(Proceedings of the Switzerland-Japan Workshop on New Directions in Cellular and Tissue Biomechanics)(Special Issue on Bioengineering)
- "MYOCARDIAL STUNNING"-LIKE PHENOMENON DURING A CRISIS OF PHEOCHROMACYTOMA
- Recent Advances in Molecular Pharmacology of the Histamine System : Preface
- Studies on Functional Roles of the Histaminergic Neuron System by Using Pharmacological Agents, Knockout Mice and Positron Emission Tomography
- Relationship Between Effects of Alcohol on Psychomotor Performances and Blood Alcohol Concentrations
- Effects of Benzylidenecyclopentanone Analogues of Curcumin on Histamine Release from Mast Cells
- Vanadium-containing Silsesquioxane-catalyzed Photo-assisted Oxidation of Hydrocarbons
- Nuclear Receptors as Targets for Drug Development : Peroxisome Proliferator-Activated Receptor γ in Mast Cells : Its Roles in Proliferation and Differentiation
- Decreased Response of Plasma Catecholamine to Stress in Diabetic Rats
- 超低出生体重児における難治性低血圧に対する低容量バゾプレッシン投与について
- Molecular Phylogeny Inferred from Sequences of Small Subunit Ribosomal DNA, Supports the Monophyly of the Metazoa
- A New Peptide-N^4-(acetyl-β-glucosaminyl)asparagine Amidase from Soybean (Glycine max)Seeds:Purification and Substrate Specificity
- Dynamic Characteristics of the Force Generated by the Outer Hair Cell Motility in the Organ of Corti : Theoretical Consideration(Bioengineering)
- Do Mucosal Mast Cells Contribute to the Immediate Asthma Response?
- Binding Characteristics of a Histamine H3-Receptor Antagonist, [3H]S-Methylthioperamide: Comparison with [3H](R)α-Methylhistamine Binding to Rat Tissues
- The Release and Subsequent Synthesis of Histamine in a Transfected Subclone of Rat Basophilic Leukemia Cells That Expresses Human Muscarinic ml Receptors
- Histamine Release Induced by Immobilization, Gentle Handling and Decapitation From Mast Cells and Its Inhibition by Nedocromil in Rats
- In situ Turgor Stability in Grape Mesocarp Cells and Its Relation to Cell Dimensions and Microcapillary Tip Size and Geometry
- Immunocytochemical localization of s-GOT and m-GOT in rat retina and brain
- Organic Field-Effect Transistor Materials Based on Cycloalkane-Capped Tetrathiapentalene Derivatives
- A report from the committee on microbroth dilution antimicrobial susceptibility testing : Issues in antimicrobial susceptibility testing of Haemophilus influenzae : a comparison of the Japanese Society of Chemotherapy lysed horse blood and the CLSI HTM br
- Inkjet Printing of Graphene Nanoribbons for Organic Field-Effect Transistors
- S01 Auditory Mechanics
- Occurrence of Late Acquired Peri-Stent Contrast Staining
- Evaluation of Camellia sinensis Catechins as a Swine Antimicrobial Feed Additive that does not Cause Antibiotic Resistance
- Dancing of auditory sensory cells
- Clinical Features of Myocardial Infarction in Young Japanese Patients
- Recurrent Spontaneous Coronary Artery Dissection Observed With Multiple Imaging Modalities
- Self Contact Organic Transistors
- A highly stereoselective synthesis of (E)-enol lactones by the Wittig reaction of cyclic anhydrides with (.ALPHA.-alkoxycarbonyl-ethylidene)triphenylphosphorane.
- Effects of .ALPHA.-fluoromethylhistidine on increase in histidine decarboxylase activity of maternal mouse kidney observed during late pregnancy and evidence for its non-mast cell origin by using estrogen and W/WV mice.
- Dependency of histamine induced phasic and tonic contractions on intracellular and extracellular calcium in guinea pig tracheal smooth muscle.
- Effects of Inhibitors of Protein Kinase C on the Release and Synthesis of Histamine in Rat Basophilic Leukemia Cells (2H3).
- Organ Assimilation of Peptides
- Regional changes in brain histamine levels following dietary-induced thiamine deficiency in rats.
- A new method for the synthesis of 3,5-disubstituted 2(5H)-furanones. Synthesis of (.+-.)-acarenoic acid.
- Functional Expression of Prestin, the Outer Hair Cell Motor Protein, Using the Baculovirus/Insect Cell System
- Functional expression of H1-histaminergic receptors in Xenopus laevis oocytes injected with bovine adrenal medullary mRNA.
- Evaluation of Camellia sinensis Catechins as a Swine Antimicrobial Feed Additive that does not Cause Antibiotic Resistance
- A CASE OF CLOSED DORSAL DISLOCATION OF THE SECOND AND THIRD CARPOMETACARPAL JOINTS WITHOUT ASSOCIATED FRACTURE
- A CASE REPORT OF TRAUMATIC ASPHYXIA CAUSED BY THE PATIENT'S OWN UPPER LIMBS