Active Force Generated by the Motility of the Outer Hair Cell(Proceedings of the Switzerland-Japan Workshop on New Directions in Cellular and Tissue Biomechanics)(Special Issue on Bioengineering)
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概要
- 論文の詳細を見る
Although the force production of the outer hair cell (OHC) leads to the fine tuning of the mammalian cochlea, the value of the force generated by the motility of the OHC in vivo has not been clarified yet. In this study, first, the active force generated by the motility of the load-free OHC in response to an electrical stimulation was measured from the deflection of the force probe. Next, to establish cell conditions similar to those of the intact cochlea, a compressive load was applied to the OHC using a force probe driven by a bimorph actuator, and then the active force generated by the motility of the loaded OHC was determined. Comparing the active force generated by the motility of the load-free OHC with that by the motility of the loaded OHC, it was found that the active force decreased due to application of the compressive load.
- 一般社団法人日本機械学会の論文
- 2002-12-15
著者
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WADA HIROSHI
Department of Surgery, Graduate School of Medicine, Osaka University
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Wada Hiroshi
Department Of Cardiovascular Science And Medicine Chiba University Graduate School Of Medicine
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Sugawara Michiko
Department of Mechanical and Environmental Informatics, Tokyo Institute of Technology
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Sugawara Michiko
Department Of Mechanical And Environmental Informatics Tokyo Institute Of Technology
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Sugawara Michiko
Department Of Mechanical Engineering Tohoku University
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MIYAMOTO Daisuke
Department of Mechanical Engineering, Tohoku University
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Miyamoto Daisuke
Shibuya Kyoiku Gakuen Senior & Junior High School
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Wada Hiroshi
Department Of Bioengineering And Robotics Tohoku University
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Wada Hiroshi
Department Of Mechanical Engineering Tohoku University
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