1. Clinical Effects of Prednisolone Suppositories (AS-1 Suppositories) on Ulcerative Colitis
スポンサーリンク
概要
- 論文の詳細を見る
Prednisolone suppositories were administered in treating 192 cases of ulcerative colitis and8 cases of radiation colitis. In both these types of colitis, main active lesion were in the rectum and sigmoid colon.<BR>The following results were obtained :<BR>1. Ulcerative colitis<BR>Mucous blood in the feces and bloody diarrhea had disappeared in 90 cases (47 %) after two weeks, and in 134 cases (70 %) after four weeks of administering the suppositories, by which time improvement of symptoms had developed in 176 cases (92 %). Deterioration was observed in only one case (0.5 %).<BR>On the colonofiberscopic examination in these cases, however, complete remission could be?found in only 57 cases (36 %), and improvement of mucosal changes in only 89 cases (56 %) even after eight weeks. Deterioration was not observed.<BR>2. Radiation colitis<BR>Mucous blood on the feces and bloody diarrhea had disappeared in 5 of the 8 cases after two weeks of administering suppositories, but colonofiberscopy revealed that a decrease in inflammation, erosion and bleeding had occurred in only one case after the same period of time.<BR>3. There was no adverse reaction except in two cases, in which partial stimulation for rectum occurred, <BR>To sum up, this suppository is extremely effective in treatment of ulcerative colitis. While it is being administered, however, regular or periodic endoscopic examinations should be made to confirm whether dosage might be decreased or suspended altogether, because of the long period of time between the disappearance of bloody feces and the achievement of endoscopic remission.
- 日本大腸肛門病学会の論文
著者
関連論文
- 胆嚢,肝門部胆管癌に対する手術術式の評価と今後の課題(第39回日消外総合シンポ2・根治性およびQOLからみた消化器癌各術式の評価(肝胆膵))
- 特集 10 拡大膵全摘術後の問題点
- 選択的動脈内セクレチン注入法によりガストリノーマを完全切除しえた1例
- 2. 食道癌に対する術前療法としてのシスプラチン投与の経験(第43回食道疾患研究会)
- 肝転移巣に alpha-fetoprotein 陽性細胞を認めた多発進行胃癌の1切除例
- 示-39 食道癌切除術後に発症した術後紅皮症の成因に関する考察(第31回日本消化器外科学会総会)
- レーザードップラー血流計によるイヌ小腸粘膜, 膵, 脾局所血流連続測定の検討
- 266 レーザードップラー血流計による家兎 VX_2 肝移植腫瘍の局所血流連続測定の検討(第26回日本消化器外科学会総会)
- 86 胃癌 P_2 以上腹膜播種性転移に対する OK-432 併用 IL-2 培養リンパ球移入療法を主とした集学的治療(第38回日本消化器外科学会総会)
- 20 腹膜播種陽性胃癌に対する温熱・化学・免疫複合療法(第37回日本消化器外科学会総会)