The therapeutic effects of SQ 29, 852 and manidipine on M-SHRSP with cerebrovascular lesions:Brain and organ vascular changes (Second report)

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概要

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• SQ 29, 852 and manidipine were administered to M-SHRSP already showing cerebrovascular lesion or M-SHRSP with head enlargement seemingly an indicator of more serious brain lesions. Although blood pressures for the two groups varied after treatment, symptoms were restored immediately and angionecrosis of the vessels of brain, heart, kidneys and testes disappeared under either treatment. Furthermore, a healing process for the brain liras recognized, wherein glial scars with iron granule cells were found to be small for rats without head enlargement but to be large for rats with head enlargement.

• International Heart Journal刊行会の論文

著者

• Okamoto Kozo

  Department Of Palhology Faculty Of Medicine Kyoto University

• Ohta Yoshio

  Department Of Anesthesia Faculty Of Medicine University Of Tokyo

• Chikugo Taka-aki

  Department of Pathology, Kinki University School of Medicine

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