The Therapeutic Effects of Several Anti-hypertensive Drugs and Diet on M-SHRSP:Changes in Life Spans, Blood Pressures, Plasma Hormones, Fundus Oculi and Internal Organs
スポンサーリンク
概要
- 論文の詳細を見る
M-SHRSP, a rat strain considered as a suitable model for the study of juvenile human malignant hypertension, were subjected to a variety of treatments for hypertension. The results showed the following: 1) It should be possible, through suitable diets appropriately combined with the administration of a selection of anti-hypertensive agents involving different mechanisms, to develop marked preventive and therapeutic results even for extremely malignant hypertensive rats such as M-SHRSP. 2) SQ 29852 seems to be a better drug than captopril. 3) In malignant hypertension, factors other than the high blood pressure itself, also, seem to play a role in the occurrence of such vascular lesions as angionecrosis.
- International Heart Journal刊行会の論文
著者
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Morita Nobuko
Department Of Pathology Kinki University School Of Medicine
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Okamoto Kozo
Department Of Palhology Faculty Of Medicine Kyoto University
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Ohta Yoshio
Department Of Anesthesia Faculty Of Medicine University Of Tokyo
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Hamada Yoh
Department of Ophthalmlogy, Tondabayashi Hospital, Kinki University School of Medicine
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Shiokawa Hiroki
Department of Pathology, Kinki University School of Medicine
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Chikugo Taka-aki
Department of Pathology, Kinki University School of Medicine
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Okamoto Kozo
Department of Clinical Functional Physiology, Toho University
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