Effects of 2-Nicotinamidoethyl Nitrate (SG-75) on Dog Coronary Artery and Cat Papillary Muscle
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概要
- 論文の詳細を見る
Effects of 2-nicotinamidoethyl nitrate (SG-75) on isolated dog coronary artery and cat papillary muscle were investigated. SG-75 dosedependently relaxed the isolated coronary arterial strips contracted with potassium. Large doses of SG-75 depressed contraction of papillary muscle driven with electrical stimulation and inhibited enhancement of contraction of papillary muscle induced by calcium and isoproterenol. From these results it is suggested that SG-75 may have a weak Ca++-antagonistic action.
- International Heart Journal刊行会の論文
著者
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HORIO YUTAKA
First Department of Internal Medicine
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Araki Haruo
Department Of Pharmacology Kumamoto University
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Sakai Masanobu
Dept. Of Pharm. Kumamoto Univ. Med. School
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Takenaka Fumio
Kumamoto Women's University
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Sakanashi Matao
Department Of Pharmacology And Department Of Pediatrics School Of Medicine University Of The Ryukyus
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SAKANASHI Matao
Department of Pharmacology, Kumamoto University Medical School
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Araki Haruo
Department of Pharmacology, Kumamoto University Medical School
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HORIO Yutaka
First Department of Internal Medicine, Kumamoto University Medical School
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TAKENAKA Fumio
Kumamoto University
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