Successful Allogeneic Bone Marrow Transplantation for Diamond-Blackfan Anemia Complicated by Severe Cardiac Dysfunction due to Transfusion-Induced Hemochromatosis
スポンサーリンク
概要
- 論文の詳細を見る
A 21-year-old man who was diagnosed with Diamond-Blackfan anemia at 2 years of age came to our hospital with the hope of undergoing bone marrow transplantation (BMT). He had been red cell transfusion-dependent for about 8 years; at presentation he had transfusion-induced hemochromatosis, a subsequent low left ventricular ejection fraction (LVEF) of 43%, and diabetes mellitus requiring insulin therapy. He received unrelated BMT with reduced intensity conditioning and sufficient GVHD prophylaxis. Regardless of the cardiac dysfunction, he had an uneventful course during pre- and post-grafting periods, and is currently doing well with an improved LVEF (55%), although he is still insulin dependent.
著者
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Arima Hiroshi
Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate Sch
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Nagai Yuya
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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NAGANO Seiji
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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ITO Kiminari
Department of Hematology, Institute of Biomedical Research and Innovation
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Mori Minako
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Ito Kiminari
Department Of Cell Therapy Institute Of Biomedical Research And Innovation
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Inoue Daichi
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Tabata Sumie
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Takiuchi Yoko
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Shimoji Sonoko
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Nagano Seiji
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Kimura Takaharu
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Hashimoto Hisako
Department Of Cell Therapy Institute Of Biomedical Research And Innovation
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Matsushita Akiko
Department Of Bioengineerig Faculty Of Bioscience And Biotechnology Tokyo Institute Of Technology
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Nagai Kenichi
Department Of Hematology And Clinical Immunology Kobe City General Hospital
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Takahashi Takayuki
Department Of Biophysics And Biochemistry Graduate School Of Science University Of Tokyo
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YANAGITA Soshi
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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