Successful Treatment of POEMS Syndrome Complicated by Severe Congestive Heart Failure with Thalidomide
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概要
- 論文の詳細を見る
A 55-year-old woman was diagnosed with POEMS syndrome; however, we could not perform high-dose chemotherapy with autologous peripheral blood stem cell transplantation (auto-PBSCT) because of rapidly progressive congestive heart failure. Thus, we treated the patient with thalidomide plus dexamethasone, which brought about a marked improvement of systolic dysfunction, POEMS syndrome-related symptoms and the serum concentrations of vascular endothelial growth factor. Subsequently, we safely performed high-dose chemotherapy with auto-PBCST. This report strongly suggests that thalidomide is effective for POEMS syndrome, even if complicated by congestive heart failure which is considered to be related to POEMS syndrome.
著者
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Imai Yukihiro
Department Of Clinical Pathology Kobe City General Hospital
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Nagai Yuya
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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MORI Minako
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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KIMURA Takaharu
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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MARUOKA Hayato
Department of Clinical Laboratory, Kobe City Medical Center General Hospital
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Mori Minako
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Inoue Daichi
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Tabata Sumie
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Takiuchi Yoko
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Shimoji Sonoko
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Maruoka Hayato
Department Of Clinical Laboratory Kobe City Medical Center General Hospital
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Kimura Takaharu
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Togami Katsuhiro
Department Of Hematology And Clinical Immunology Kobe City Medical Center General Hospital
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Matsushita Akiko
Department Of Bioengineerig Faculty Of Bioscience And Biotechnology Tokyo Institute Of Technology
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Nagai Kenichi
Department Of Hematology And Clinical Immunology Kobe City General Hospital
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Kato Aiko
Department Of Agricultural Chemistry Yamaguchi University
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Takahashi Takayuki
Department Of Biophysics And Biochemistry Graduate School Of Science University Of Tokyo
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TOGAMI Katsuhiro
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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KATO Aiko
Department of Hematology and Clinical Immunology, Kobe City Medical Center General Hospital
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Kitai Takeshi
Department of Cardiology, Kobe City Medical Center General Hospital
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Beppu Minako
Department of Neurology, Kobe City Medical Center General Hospital
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Kawamoto Michi
Department of Neurology, Kobe City Medical Center General Hospital
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