Expression of Phospholipase D Isozymes in Mouse Lungs during Postnatal Development
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概要
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The expression level of phospholipase D (PLD) was examined in the lungs of mice during postnatal development. Immunoprecipitation analysis revealed a moderate basal level of PLD1 in the lungs at postnatal 1 week, with a gradual increase occurring until week 4. The pattern of PLD2 paralleled that of PLD1, although the quantity of PLD2 was markedly less. PLD was immunostained in the most bronchiolar epithelium, some pulmonary macrophages and alveolar cells at postnatal week 1, with increased immunoreactivity in those cells with lung development at postnatal week 4. These findings suggest that the increase of PLD expression is associated with pulmonary alveolarization, possibly by involvement in cell proliferation and differentiation during postnatal mouse lung development.
- 社団法人 日本獣医学会の論文
著者
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Jeong Jinwoo
Department of Electrical and Electronic Engineering, Yonsei University
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SHIN Taekyun
Department of Veterinary Medicine, Graduate School, Cheju National University
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MOON Changjong
Department of Veterinary Medicine, College of Applied Life Science and Applied Radiological Science
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Shin Min
Departments Of Preventive Medicine Chonnam National University Medical School
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MIN Do
Department of Physiology, College of Medicine, The Catholic University of Korea
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Min Do
Department Of Physiology College Of Medicine The Catholic University Of Korea
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Shin Taekyun
Department Of Veterinary Medicine Cheju National University
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Moon C
Department Of Veterinary Anatomy College Of Veterinary Medicine Chonnam National University
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Moon Changjong
Department Of Physiology University Of The Ryukyus School Of Medicine:department Of Veterinary Medic
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Shin Min
Department of Applied Science, Korea Maritime University, Busan 606-791, Korea
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MIN Do
Department of Molecular Biology, College of Natural Science, Pusan National University
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SHIN Taekyun
Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University
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SHIN Min
Department of Molecular Biology, College of Natural Science, Pusan National University
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MOON Changjong
Department of Veterinary Anatomy, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University
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JEONG Jinwoo
Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University
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