Chemical Constituents of the Bulbs of Habranthus brachyandrus and Their Cytotoxic Activities
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概要
- 論文の詳細を見る
The bulbs of Habranthus brachyandrus (Amaryllidaceae) have been extensively analyzed for their chemical constituents, resulting in the isolation of eight flavan derivatives (1—8), four of which are new naturally occurring compounds; a new hydroxybutyric acid glucoside (9); three known phenolic compounds (10—12); and six known alkaloids (13—18). The structures of the new compounds were determined on the basis of spectroscopic analysis, including two-dimensional (2D) NMR data, and chemical evidence. The isolated compounds and a few derivatives were evaluated for their cytotoxic activities against HL-60 human promyelocytic leukemia cells and HSC-2 human oral squamous cell carcinoma cells.
著者
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Sakagami Hiroshi
Department of Health and Nutrition Sciences,Tokyo Seiei College
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Sakagami H
Dep. Of Dental Pharmacology Meikai Univ. School Of Dentistry
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Sakagami H
Dep. Of Diagnostic And Therapeutic Sciences School Of Dentistry Meikai Univ.
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Yokosuka Akihito
Lab. Of Medicinal Pharmacognosy School Of Pharmacy Tokyo Univ. Of Pharmacy And Life Sciences
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MIMAKI Yoshihiro
Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Sci
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Jitsuno Maki
Laboratory of Medicinal Pharmacognosy, School of Pharmacy, Tokyo University of Pharmacy and Life Sci
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Yokosuka Akihito
Laboratory of Medicinal Pharmacognosy, School of Pharmacy, Tokyo University of Pharmacy and Life Sci
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Sakagami Hiroshi
Department Of Dental Pharmacology Meikai University School Of Dentistry
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Mimaki Yoshihiro
Laboratory Of Medical Plant Science Tokyo University Of Pharmacy And Life Science
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Sakagami Hiroshi
Department Of Biochemical Pharmacology Tokyo Metropolitan Institute Of Gerontology
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Yokosuka Akihito
Laboratory Of Medicinal Pharmacognosy School Of Pharmacy Tokyo University Of Pharmacy And Life Scien
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Yokosuka Akihito
Laboratory Of Medicinal Pharmacognosy School Of Pharmacy Tokyo University Of Pharmacy And Life Scien
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Jitsuno Maki
Lab. Of Medicinal Pharmacognosy School Of Pharmacy Tokyo Univ. Of Pharmacy And Life Sciences
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