Inhibition of Lipid Accumulation in Lipomyces Yeast by 2(E), 4(E)-Decadienoic Acid from Pepper.
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概要
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Inhibitors of lipid accumulation in <I>Lipomyces starkeyi</I> were screened from various kinds of foods from the point of anti-obesity. An extract of black pepper showed inhibition of lipid accumulation with apparently weak repression of its growth. An active component was isolated from black pepper and was identified as 2(E),4(E)-decadienoic acid by instrumental analyses. Pepper contains about 20 mg/100 g of 2(E),4(E)-decadienoic acid. The minimum inhibitory concentrations of 2(E),4(E)-decadienoic acid against microbial growth ranged from 60 to 1000 μg/ml. The acid inhibited the growth of <I>L. starkeyi </I>at 100 μg/ml and the lipid accumulation at 12-50 μg/ml. The repression of lipid accumulation in <I>L. starkeyi </I>by 2(E),4(E)-decadienoic acid seemed to be due to the inhibition of glycerol-3-phosphate dehydrogenase and growth.
- 社団法人 日本食品科学工学会の論文
著者
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Murata Masatsune
Department Of Nutrition & Food Science Ochanomizu University
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Irie Junko
Department Of Nutrition And Food Chemistry Ochanomizu Unibersity:phermaceutical Research Institute K
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HOMMA Seiichi
Department of Bioscience, Tokyo University of Agriculture
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IRIE Junko
Department of Nutrition and Food Science, Ochanomizu University
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MORITA Yoshie
Department of Nutrition and Food Science, Ochanomizu University
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