Localization of the Candidate Genes ELOVL5 and SCD1 for 'Male Effect' Pheromone Synthesis in Goats (Capra hircus)
スポンサーリンク
概要
- 論文の詳細を見る
The ‘Male-Effect’ is a well-known phenomenon in female sheep and goats, whereby pheromone-induced activation of reproductive function occurs. In a previous study, we showed that the genes for elongation of long-chain fatty acids family member 5 (ELOVL5) and stearoyl-CoA desaturase 1 (SCD1) increased their expression significantly, concomitant with induction of pheromone synthesis. Therefore, these genes were considered to be prime candidate genes for pheromone synthesis. In the present study, we performed in situ hybridization to investigate where these two genes are expressed in goat skin. Strong positive signals were detected for both genes in the head skin of the male goat, which is the main site of pheromone production, and were mainly in the basal layer of the sebaceous gland cells, with the remaining cells showing negligible signals. None of the cells in the rump skin of the male goat or the head skin of the orchidectomized goat, neither of which produce pheromone, exhibited strong positive signals. The present study demonstrates that expression of these two candidate genes for pheromone synthesis is primarily localized in the sebaceous glands of the pheromone-producing skin region.
- 日本繁殖生物学会の論文
- 2007-12-01
著者
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菊水 健史
麻布大学・獣医・伴侶動物
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MORI Yuji
Laboratory of Veterinary Ethology, The University of Tokyo
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MOMOZAWA Yukihide
Laboratory of Veterinary Ethology, The University of Tokyo
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KIKUSUI Takefumi
Laboratory of Veterinary Ethology, The University of Tokyo
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TAKEUCHI Yukari
Laboratory of Veterinary Ethology, The University of Tokyo
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Mori Y
Laboratory Of Veterinary Ethology The University Of Tokyo
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Masuda Koji
Laboratory Of Veterinary Ethology The University Of Tokyo
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KITAGO Masaru
Laboratory of Veterinary Ethology, The University of Tokyo
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WAKABAYASHI Yoshihiro
Laboratory of Veterinary Ethology, The University of Tokyo
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DATE ITO
Laboratory of Veterinary Ethology, The University of Tokyo
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HAGINO YAMAGISHI
Single Molecule Project, Tokyo Metropolitan Institute of Medical Science
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Date Ito
Laboratory Of Veterinary Ethology The University Of Tokyo
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Kitago Masaru
Laboratory Of Veterinary Ethology The University Of Tokyo
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Mori Yuji
Univ. Tokyo Tokyo Jpn
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Mori Yuji
Laboratory Of Veterinary Ethology The University Of Tokyo
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Hagino Yamagishi
Single Molecule Project Tokyo Metropolitan Institute Of Medical Science
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Takeuchi Yukari
Laboratory Of Veterinary Ethology The University Of Tokyo
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Momozawa Yukihide
Laboratory Of Veterinary Ethology University Of Tokyo
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Wakabayashi Yoshihiro
Department Of Ultrastructural Research Tokyo Metropolitan Institute Of Medical Science
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Wakabayashi Yoshihiro
Laboratory Of Neurobiology National Institute Of Agrobiological Sciences
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Mori Yuji
Laboratory Of Veterinary Ethology Animal Resource Science The University Of Tokyo
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Mori Yuji
Laboratory of Physical Chemistry Tokyo Institute of Technology
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