Degradation of PrP^<Sc> by Keratinolytic Protease from Nocardiopsis sp. TOA-1

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概要

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• A keratinolytic alkaline proteae (NAPase) from Nocardiopsis sp. TOA-1 degraded a scrapie prion without any chemical or physical treatment. Optimal temperature and pH were 60 °C and above pH 10.0. The scrapie prion was completely degraded within 3 min under optimal conditions.

• 社団法人 日本農芸化学会の論文
• 2006-05-23

著者

• ZHAO Hui

  Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine

• OKA Tatsuzo

  Department of Nutritional Chemistry, University of Tokushima School of Medicine

• Oka Tatsuzo

  Kagoshima Univ. Kagoshima

• Sakai Masashi

  Department Of Cardiovascular Science And Medicine Chiba University Graduate School Of Medicine

• 古川 謙介

  別府大

• 古川 謙介

  別府大・食物栄養

• MITSUIKI Shinji

  Department of Agricultural Chemistry, Kyushu University

• Zhao Hui

  Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine

• Oka Tatsuzo

  Department Of Veterinary Physiology Kagoshima University

• Oka Tatsuzo

  Department Of Nutrition School Of Medicine The University Of Tokushima

• FURUKAWA Kensuke

  Division of Bioresource and Bioenvironmental Sciences, Kyushu University

• Mitsuiki S

  Kyushu Sangyo Univ. Fukuoka Jpn

• Mitsuiki Shinji

  Department Of Applied Chemistry And Biochemistry Kyushu Sangyo University

• MATSUMOTO Daishi

  Department of Applied Chemistry and Biochemistry, Kyushu Sangyo University

• MORIYAMA Yasushi

  Fundamental Research Center, TOTO Ltd.

• KANOUCHI Hiroaki

  Department of Biochemistry, Kawasaki Medical School

• Furukawa Kensuke

  Division Of Bioresource And Bioenvironmental Sciences Kyushu University

• Furukawa Kensuke

  Graduate School Of Bioresource And Bioenvironmental Sciences Kyushu University

• Moriyama Yasushi

  Fundamental Research Laboratory Toto Ltd.

• Moriyama Yasushi

  Fundamental Research Center Toto Ltd.

• Mitsuiki Shinji

  Department Of Agricultural Chemistry Kyushu University

• Zhao Hui

  Department Of Veterinary Physiology Kagoshima University

• Furukawa K

  Graduate School Of Bioresource And Bioenvironmental Sciences Kyushu University

• Sakai M

  Department Of Applied Chemistry And Biochemistry Kyushu Sangyo University

• Moriyama Y

  Fundamental Research Center Toto Ltd.

• Kanouchi Hiroaki

  Department Of Biochemistry Kawasaki Medical School

• Kanouchi Hiroaki

  Kagoshima Univ. Kagoshima

• Matsumoto Daishi

  Department Of Applied Chemistry And Biochemistry Kyushu Sangyo University

• Sakai Masashi

  Department Of Biology Washington University

• Hui Zhao

  Department of Veterinary Physiology, Kagoshima University

• SAKAI Masashi

  Department of Applied Chemistry and Biochemistry, Kyushu Sangyo University

• OKA Tatsuzo

  Department of Frontier Veterinary Science, Faculty of Agriculture, Kagoshima University

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