Na^+-Dependent Transport System for Taurocholate in Rat Small Intestine : Its Localization in the Terminal Ileum and Variation by Fasting(Food & Nutrition)

概要

論文の詳細を見る
The uptake of taurocholate in rat small intestine was investigated with everted sacs and epithelial cells. It was ascertained by means of these assay systems that Na^+-dependent taurocholate transport would be confined to the distal ileum. The effect of fasting on the Na^+-dependent taurocholate transport was assessed using isolated epithelial cells from there. Fasting for 2 days led to a considerable decrease in the taurocholate uptake by the epithelial cells regardless of Na^+-dependent or -independent transport. When kinetic parameters (K_t, V_<max>) were obtained for net Na^+-dependent taurocholate transport from double-reciprocal plots of the taurocholate concentration against its corresponding transport rate, these values suggested that a diminution not in the affinity for taurocholate but in the quantity of "carrier" protein would have arisen from semi-starvation.
社団法人日本農芸化学会の論文
1990-03-23