Solvolytic Behavior of O-(1-Cyclopropylethyl) S-Methyl Dithiocarbonate and Related Compounds(Organic,Chemical)
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概要
- 論文の詳細を見る
O-(1-Cyclopropylethyl) S-methyl dithiocarbonate (Ib) was solvolyzed in various solvents to give S-(1-cyclopropylethyl) S-methyl dithiocarbonate (IIb) quantitatively. The reaction obeyed the first-order rate law and the rates were considerably affected by the polarity of the solvent used. Phenolysis of Ib with p-chlorophenol gave IIb and a small amount of the phenol ether. Plots of the logarithm of the reaction rates against Y values gave a linear relationship. The reaction was found to be markedly accelerated by phenolic solvents. The rate in p-chlorophenol is 509 times faster than that in ethanol. The role of hydrogen-bonding to the thione sulfur in the rearrangement reaction is discussed.
- 公益社団法人日本薬学会の論文
- 1987-04-25
著者
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原野 一誠
Faculty of Pharmaceutical Sciences, Kumamoto University
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久野 拓造
Faculty Of Pharmaceutical Sciences Kumamoto University
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原野 一誠
熊本大学 薬
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原野 一誠
熊本大学薬学部
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久野 拓三
熊本大学薬学部
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清永 秀雄
Faculty of Pharmaceutical Sciences, Kumamoto University
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清永 秀雄
Faculty Of Pharmaceutical Sciences Kumamoto University
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