Reaction of Aromatic N-Oxides with Dipolarophiles. VIII. Carbamation Products of 2-Anilinopyridine Derivatives

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概要

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• In the 1,3-dipolar cycloaddition reaction of pyridine N-oxides with phenyl isocyanates, we have isolated 1,5-sigmatropy products of the primary cycloadduct and carbamation products of 2-anilinopyridines. In connection with the tautomerism of 2-anilinopyridines, the structure of the carbamation products is discussed in detail based on kinetic, molecular orbital calculation and spectral data. A comparison of the spectral data with those of structurally related compounds indicated that the carbamation dose not occur at the ring nitrogen but at the exocyclic one.

• 公益社団法人日本薬学会の論文
• 1985-05-25

著者

• 松岡 俊和

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 末松 文博

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 原野 一誠

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 久野 拓造

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 原野 一誠

  熊本大学 薬

• 原野 一誠

  熊本大学薬学部

• 久野 拓三

  熊本大学薬学部

• 大泉 憲秀

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 大泉 憲秀

  Faculty Of Pharmaceutical Sciences Kumamoto University

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