Preparation of Carbon Nanotube-alginate Nanocomposite Gel for Tissue Engineering
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概要
- 論文の詳細を見る
A novel scaffold material based on an alginate hydrogel which contained carbon nanotubes (CNTs) was prepared, and its mechanical property and biocompatibility evaluated. Soluble CNTs were prepared with acid treatment and dispersed in sodium alginate solution as a cross-linker. After which, the mechanical property (elastic deformation), saline sorption, histological reaction, and cell viability of the resultant nanocomposite gel (CNT-Alg gel) were evaluated. The CNT-Alg gel showed faster gelling and higher mechanical strength than the conventional alginate gel. Saline sorption amount of freeze-dried CNT-Alg gel was equal to that of the alginate gel. In terms of histological evaluation and cell viability assay, CNT-Alg gel exhibited a mild inflammatory response and non-cytotoxicity. These results thus suggested that CNT-Alg gel could be useful as a scaffold material in tissue engineering with the sidewalls of CNTs acting as active sites for chemical functionalization.
- 日本歯科理工学会の論文
著者
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HAYAKAWA Toru
Department of Neurosurgery, Osaka University Medical School
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Taniguchi Kunihisa
Department Of Morphological Biology Pathology Section Fukuoka Dental College
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NAKASHIMA Naotoshi
Department of Applied Chemistry, Kyushu University
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Inoue Yusuke
Fukuoka College Of Health Sciences
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FUKUSHIMA Tadao
Department of Dental Engineering, Bioengineering section, Fukuoka Dental College
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KAWAGUCHI Minoru
Department of Dental Engineering, Bioengineering section, Fukuoka Dental College
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Hayakawa Tohru
日本大学松戸歯学部 歯科生体材料学
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Hayakawa Toru
Department Of Biochemistry Akita University School Of Medicine
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TAKEDA Shoji
Department of Biomaterials, Osaka Dental University
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KAWAGUCHI Minoru
Bioengineering Section, Department of Dental Engineering, Fukuoka Dental College
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FUKUSHIMA Tadao
Bioengineering Section, Department of Dental Engineering, Fukuoka Dental College
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OKAMURA Kazuhiko
Pathology Section, Department of Morphological Biology, Fukuoka Dental College
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TANIGUCHI Kunihisa
Pathology Section, Department of Morphological Biology, Fukuoka Dental College
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Fukushima Tadao
Associate Professor Department Of Dental Engineering Biomaterials Section Fukuoka Dental College
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Takeda Shoji
Department Of Biomaterials Osaka Dental University
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Fukushima Tadao
Department Of Dental Engineering Fukuoka Dental College
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Kawaguchi Minoru
Department Of Dental Engineering Bioengineering Section Fukuoka Dental College
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Okamura Kazuhiko
Pathology Section Department Of Morphological Biology Fukuoka Dental College
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Taniguchi Kunihisa
Section Of Pathology Department Of Morphological Biology Division Of Pathology Department Of Morphol
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Taniguchi Kunihisa
Pathology Section Department Of Morphological Biology Fukuoka Dental College
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Nakashima Naotoshi
Department Of Applied Chemistry Graduate School Of Engineering Kyusyu University
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Nakashima Naotoshi
Department Of Applied Chemistry Faculty Of Engineering Kyushu University
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