Cytocompatibility of osteoblast-like cells to fiber-sintered porous titanium
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概要
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Titanium of 30, 40, and 50% porosity has been developed to create a firm bond between the dental implant and bone. We examined its cytocompatibility with osteoblast-like cells by evaluating cell viability and alkaline phosphatase (ALP) activity in vitro. Cell viability after 1 day of culture was lower with the three types of porous titanium than with polished titanium. After 14 days of culture, the three porous titanium samples showed a level of cell viability similar to that of polished titanium. However, cell viability decreased with increasing porosity. The highest level of ALP activity was found on 30% porosity titanium after 7 and 14 days of culture. Cells penetrated the 50% porosity titanium. The results suggest that porous titanium promotes osteoblast proliferation and differentiation.
- 大阪歯科学会の論文
著者
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Ueda Akihiro
Department Of Geriatric Dentistry Osaka Dental University
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Ueda Akihiro
Department Of Biomaterials Osaka Dental University
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Ueda Akihiro
Department Of Applied Chemistry And Biochemistry Faculty Of Engineering Kumamoto University
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NAKAMURA Masaaki
Department of Biomaterials, Osaka Dental University
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TAKEDA Shoji
Department of Biomaterials, Osaka Dental University
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Takeda Shoji
Department Of Biomaterials Osaka Dental University
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Nakamura Masaaki
Department Of Applied Physics Faculty Of Science Tokyo University Of Science
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