Novel In Vitro Screening System for Monoclonal Antibodies Using Hypermutating Chicken B Cell Library(METHOD)
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概要
- 論文の詳細を見る
Here, we report an in vitro screening system for monoclonal antibodies using a hypermutating chicken B cell line, DT40-SW. When switching on hypermutation, cultured DT40-SW cells constituted an antibody library, from which clones secreting antibodies to a test antigen were successfully isolated, and genetically stabilized by switching off the mutation machinery.
- 社団法人日本生物工学会の論文
- 2006-11-25
著者
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Magari Masaki
Department of Bioscience and Biotechnology, Graduate School of Natural Science and Technology, Okaya
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Todo Kagefumi
Department of Bioscience and Biotechnology, Graduate School of Natural Science and Technology, Okaya
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Kanayama Naoki
Department of Bioscience and Biotechnology, Graduate School of Natural Science and Technology, Okaya
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Ohmori Hitoshi
Department of Bioscience and Biotechnology, Graduate School of Natural Science and Technology, Okaya
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Kanayama Naoki
Department Of Bioscience And Biotechnology Graduate School Of Natural Science And Technology Okayama
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Todo Kagefumi
Department Of Bioscience And Biotechnology Graduate School Of Natural Science And Technology Okayama
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Miyake Kenji
Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University
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Miyake Kenji
Department Of Biotechnology Graduate School Of Natural Science And Technology Okayama University
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Magari Masaki
Department Of Bioscience And Biotechnology Graduate School Of Natural Science And Technology Okayama
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Ohmori Hitoshi
Department Of Bioscience And Biotechnology Graduate School Of Natural Science And Technology Okayama
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