Incidence and Outcome of Sepsis in Japanese Intensive Care Units : The Japanese Nosocomial Infection Surveillance System

スポンサーリンク

概要

• 論文の詳細を見る

• Objectives: To determine the incidence of sepsis in Japanese intensive care units (ICUs) and to evaluate the impact of sepsis on mortality and length of stay (LOS). Methods: Using the JANIS database for the period between June 2002 and June 2004, 21,895 eligible patients aged ≥16 years, hospitalized in 28 participating ICUs for ≥24 hours, were monitored until ICU discharge. Adjusted hazard ratio (HR) with 95% confidence interval (CI) for the incidence of sepsis was calculated using Cox's proportional hazard model. Standardized mortality ratio (SMR) was calculated on the basis of the crude mortality in patients without nosocomial infection (NI) for respective APACHE II categories. Mean LOS for survivors was assessed by two-way analysis of variance with adjustment for APACHE II. Results: Sepsis was diagnosed in 450 patients (2.1%), with 228 meeting the definition on ICU admission and 222 during the ICU stay. The overall incidence of sepsis was 1.02/100 admissions or 2.00/1000 patient-days. A significantly higher HR for the incidence of sepsis was found in men (1.54, 95% CI: 1.14-2.07), APACHE II≥21 (2.92, 95% CI: 1.92-4.44), ventilator use (3.30, 95% CI: 1.98-5.49), and central venous catheter use (3.45, 95% CI: 1.90-6.28). SMR was determined to be 1.18 (95% CI: 0.82-1.21) in NI patients without sepsis and 2.43 (95% CI: 1.88-3.09) in NI patients with sepsis. Mean LOS for survivors was calculated to be 11.8 days (95% CI: 11.3-12.4) in NI patients without sepsis and 15.0 days (95% CI: 13.3-17.0) in NI patients with sepsis compared with 3.8 days (95% CI: 3.8-3.9) in patients without NI. Conclusions: Sepsis is not very common in Japanese ICUs, but its development leads to further increases in mortality and LOS in patients with NI.

• 日本衛生学会の論文

著者

• YOSHIDA Katsumi

  Department of Clinical and Laboratory Medicine, Tohoku University School of Medicine

• Yoshida K

  Department Of Preventice Medicine St. Marianna University School Of Medicine

• Suka Machi

  Department Of Preventive Medicine St Marianna University School Of Medicine

• TAKEZAWA Jun

  Department of Emergency and Intensive Care Medicine, Nagoya University Graduate School of Medicine

• Takezawa Jun

  Department Of Emergency And Intensive Care Medicine Nagoya University Graduate School Of Medicine

• Sekine Michikazu

  Department Of Welfare Promotion And Epidemiology Graduate School Of Medicine And Pharmaceutical Scie

関連論文

• Hyperthyroid Graves' Disease and Primary Hypothyroidism Caused by TSH Receptor Antibodies in Monozygotic Twins : Case Reports
• Failure in Detection of Epstein-Barr Virus and Cytomegalovirus in Specimen Obtained by Fine Needle Aspiration Biopsy of Thyroid in Patients with Subacute Thyroiditis
• Years of Potential Life Lost as the Indicator of Premature Mortality in Occupational Medicine
• Assisting the Diagnosis of Thyroid Diseases with Bayesian-Type and SOM-Type Neural Networks Making Use of Routine Test Data
• 11-O-28 Mechanical Properties of Beta-Tricalcium Phosphate Doped with Metal Ions
• 日本人の思春期の女性におけるボディイメージと生活習慣との関係
• Evaluation of hematuria using the urinary albumin-to-total-protein ratio to differentiate glomerular and nonglomerular bleeding
• Thyroid Hormone Regulates Rat Placental Type III Iodothyronine Deiodinase Activity by Inducing Kinetic Changes Different from Those in the Same Isozyme in Rat Brain
• Acceptability and Long-Term Compliance with Drug Treatment for Hypercholesterolemia in Japanese Male Workers : I. Acceptability of Drug Treatment
• Acceptability and Long-Term Compliance with Drug Treatment for Hypercholesterolemia in Japanese Male Workers : II. Long-Term Compliance with Drug Treatment
• Autonomously Functioning Thyroid Nodule Associated with Thyrotoxic Periodic Paralysis
• Development of Subclinical Hyperthyroidism due to Graves' Disease in a Hypothyroid Woman who had Undergone Hemithyroidectomy for Adenomatous Goiter and Radiotherapy for Nasopharyngeal Cancer
• Multiple Risk Factors Syndrome in Japanese Male Subjects Using Automatic Multiphasic Health Testing and Service Data : A Work-site Cohort Study
• The Relationship between New Stroke Onset and Serum Thiocyanate as an Indicator to Cigarette Smoking
• Serum Thiocyanate Concentration as an Indicator of Smoking in Relation to Deaths from Cancer
• Sunitinib-Induced Thyrotoxicosis Followed by Persistent Hypothyroidism with Shrinkage of Thyroid Volume
• Re-evaluation of the latent period of bladder cancer in dyestuff-plant workers in Japan
• Lifestyle and Overweight Among Japanese Adolescents : The Toyama Birth Cohort Study
• Health Examinations Should Expand Their Scope to Musculoskeletal Conditions : Estimation of Burden of Musculoskeletal Pain on AMHTS Population in Terms of Prevalence and Interference with Daily Activities
• Parental Obesity, Lifestyle Factors and Obesity in Preschool Children : Results of the Toyama Birth Cohort Study
• Characteristic Lifestyles in 6-year-old Children with Obese Parents : Results of the Toyama Birth Cohort Study
• Influence of Behavioral and Environmental Factors on the Development of Obesity in Three-year-old Children -A Case-Control Study Based on Toyama Study-
• Validity of Child Sleep Diary Questionnaire among Junior High School Children
• Validation of a Self-reported Physical Activity Questionnaire for Schoolchildren
• Associations of Sense of Coherence with Sickness Absence and Reported Symptoms of Illness in Japanese Civil Servants
• Job Strain and Sleep Quality in Japanese Civil Servants with Special Reference to Sense of Coherence
• Accuracy of the Estimated Prevalence of Childhood Obesity from Height and Weight Values Reported by Parents : Results of the Toyama Birth Cohort Study
• Validity of a Questionnaire Evaluating Physical Activity Level in Young Children
• A Meta-analysis of Epidemiological Studies on the Relationship between Occupational Electromagnetic Field Exposure and the Risk of Adult Leukemia
• 3歳から6歳時における小児の body mass index に影響する環境行動要因の検討 : 富山コホートスタディ
• Association between Insomnia and Hypertension in Japanese Male Workers
• Association of Smoking Behavior and Socio-Demographic Factors, Work, Lifestyle and Mental Health of Japanese Civil Servants
• Study of a Mortality Surge among Transport Workers in Japan
• Intra-Individual Variability of High-Sensitivity C-Reactive Protein : Age-Related Variation Over Time in Japanese Subjects(CLINICAL INVESTIGATION)
• Effect of Moderate Alcohol Intake on Nocturnal Sleep Respiratory Parameters in Healthy Middle-Aged Men
• Association between Sense of Coherence and Heart Rate Variability in Healthy Subjects
• Adverse Health Experience in Male Workers during the Boom Economy in Japan
• Nested Case-Control Study on Associations between Lung Function, Smoking and Mortality in Japanese Population
• Body Image, Body Satisfaction and Dieting Behavior in Japanese Preadolescents : The Toyama Birth Cohort Study
• Body Image and Body Satisfaction Play Important Roles in the Path to Dieting Behavior in Japanese Preadolescents : The Toyama Birth Cohort Study
• Association between APACHE II Score and Nosocomial Infections in Intensive Care Unit Patients:A Multicenter Cohort Study
• Impact of Intensive Care Unit-Acquired Infection on Hospital Mortality in Japan: A Multicenter Cohort Study
• The Relationship between New Stroke Onset and Serum Thiocyanate as an Indicator to Cigarette Smoking
• Standard Protocol for Exchange of Health-Checkups Based on SGML : The Health-Checkups Data Markup Language (HDML)
• The Validity of Nursery Teachers' Report on the Physical Activity of Young Children
• Parental Influence on the Development of Obesity in 9-year-old Japanese Children : the Toyama Birth Cohort Study
• Job Strain Does Not Relate to Morning Level Vanilmandelic Acid in Japanese Civil Servants
• Impact of Intensive-Care-Unit(ICU)-Acquired Ventilator-Associated Pneumonia(VAP) on Hospital Mortality : A Matched-Paired Case-Control Study
• Insomnia is Associated with Psychological and Physical Problems in Japanese Male Workers
• A Novel EEG Index for Evaluating the Sleep Quality in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome
• Epidemiological approach to nosocomial infection surveillance data : the Japanese Nosocomial Infection Surveillance System
• Incidence and Outcome of Sepsis in Japanese Intensive Care Units : The Japanese Nosocomial Infection Surveillance System
• Persistent Insomnia is a Predictor of Hypertension in Japanese Male Workers
• Smoking status in Japanese mothers before and after childbirth in an urban area
• The Impacts of Health Examinations and Smoking on Disease Mortality Risk in Japan : a Longitudinal Cohort of 720,611 Japanese Life Insured Persons
• Risk Factors of Low APGAR Score in Japanese Full-term Deliveries : A Case-control Study
• Preventive Strategy for Hypertension Based on Attributable Risk Measures
• Application of the Updated Framingham Risk Score to Japanese Men
• Obesity and Cardiac Autonomic Nerve Activity in Healthy Children : Results of the Toyama Birth Cohort Study
• Acute Mercury Poisoning by Intentional Ingestion of Mercuric Chloride
• A Study of the Reliability of Health State Valuations in the Japanese Euro Qol Instrument
• Cost-effectiveness Analysis of Prostate Cancer Screening
• BMI, waist circumference, and clustering of cardiovascular risk factors in Japanese adults
• Erythrocyte zinc concentration as an indicator to distinguish painless thyroiditis-associated transient hypothyroidism from permanent hypothyroidism
• Explaining global job satisfaction by facets of job satisfaction : the Japanese civil servants study
• Does the Japanese Society for Hygiene need its own Code of Conduct? A comparison of the responses of councilors and junior members based on a questionnaire survey
• Low back pain deprives the Japanese adult population of their quality of life : a questionnaire survey at five healthcare facilities in Japan
• Establishment of a Method to Detect Microalbuminuria by Measuring the Total Urinary Protein-to-Creatinine Ratio in Diabetic Patients
• Accuracy of the Estimated Prevalence of Childhood Obesity from Height and Weight Values Reported by Parents : Results of the Toyama Birth Cohort Study
• Parental Obesity, Lifestyle Factors and Obesity in Preschool Children : Results of the Toyama Birth Cohort Study
• Severity-based treatment for Japanese patients with MPO-ANCA-associated vasculitis : the JMAAV study
• Effects of Thyroid Hormone on Erythrocyte Carbonic Anhydrase-I and Zinc Concentrations In Vivo and In Vitro : Clinical Usefulness of Carbonic Anhydrase-I and Zinc Concentrations in Erythrocytes
• Association of Sleep Quality and Free Time Leisure Activities in Japanese and British Civil Servants
• Improvement in health-related quality of life in MPO-ANCA-associated vasculitis patients treated with cyclophosphamide plus prednisolone : an analysis of 18 months of follow-up data from the JMAAV study
• N-terminal pro-Brain Natriuretic Peptide as a Predictor of Reoperation in Children With Surgically Corrected Tetralogy of Fallot
• STUDIES ON THE SENSITIVITY OF PATHOGENIC STAPHYLOCOCCI TO ANTIBIOTICS WITH SPECIAL REFERENCE TO THE PENICILLIN-RESISTANT STRAINS
• Occupational Class Differences in Body Mass Index and Weight Gain in Japan and Finland
• Primary membranoproliferative glomerulonephritis on the decline : decreased rate from the 1970s to the 2000s in Japan
• The 14-item health literacy scale for Japanese adults (HLS-14)

もっと見る 閉じる

スポンサーリンク