Job Strain Does Not Relate to Morning Level Vanilmandelic Acid in Japanese Civil Servants
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概要
- 論文の詳細を見る
Epidemiologic and clinical studies have related acute and, less frequently, chronic life stress to cardiovascular diseases.In addition, animal models suggest that chronic psychological stress could cause atherosclerosis, probably by increasing sympathetic activation.In this cross-sectional study we evaluated the association between job strain, as one of the markers of workplace stress, and the urinary excretion of Vanilmandelic acid(VMA)upon awakening as a sympathoadrenal activity marker in the morning.Subjects were 936 male and 823 female civil servants working in departments related to the municipality of a city in Toyama Prefecture, Japan, in the spring of 2001.VMA was measured by highperformance liquid chromatography.We found that there was an age dependent increase in the level of VMA and females had higher VMA levels than males.Males who were current smokers had significantly lower VMA levels than nonsmokers after adjusting for age.Job strain level did not relate to VMA concentration in urine after adjusting for age and smoking status both in men and women.In addition, working and sleeping hours as predictor variables were also not associated with urinary VMA levels upon awakening in the morning.In conclusion, it seems that job strain does not independently relate to the sympathoadrenal activity, but the interaction between job strain and other variables such as personal characteristics and environmental factors and their relation with sympathoadrenal activity should further be explored.J Epidemiol2002;12:324-329.
- 日本疫学会の論文
著者
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KAGAMIMORI SADANOBU
Department of Welfare Promotion and Epidemiology, Toyama Medical and Pharmaceutical University
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Nasermoaddeli Ali
Department of Epidemiology and Public Health, Kanazawa Medical University
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Nasermoaddeli Ali
Department Of Welfare Promotion And Epidemiology Graduate School Of Medical Sciences University Of T
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ナセルモアデリ アリ
富山医科薬科大学保健医学教室
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Nasermoaddeli Ali
Department Of Epidemiology And Public Health Kanazawa Medical University
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Kagamimori S
Department Of Welfare Promotion And Epidemiology Faculty Of Medicine University Of Toyama
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Kagamimori Sadanobu
聖マリアンナ医科大学 予防医学
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Kagamimori Sadanobu
Department Of Community Medicine Faculty Of Medicine Toyama Medical And Pharmaceutical University
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Hamanishi Shimako
Department Of Welfare Promotion And Epidemiology Toyama Medical
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SEKINE Michikazu
Department of Welfare Promotion and Epidemiology, Toyama Medical and Pharmaceutical University
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Kagamimori Sadanobu
Department Of Welfare Promotion And Epidemiology Graduate School Of Medicine And Pharmaceutical Scie
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Sakai Hideo
Department Of Welfare Promotion And Epidemiology Toyama Medical
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Sekine Michikazu
Department Of Welfare Promotion And Epidemiology Graduate School Of Medicine And Pharmaceutical Scie
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KAGAMIMORI Sadanobu
Department of Community Health and Preventive Medicine, Toyama Medical and Pharmaceutical University
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SEKINE MICHIKAZU
Department of Surgery, School of Medicine, Keio University
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