BIO-MEMSを用いたダイオキシンの測定に関する研究(OS.12 機能性マイクロデバイスの創製・評価)

概要

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The Ah-Immunoassay method in a Bio-MEMS was developed and applied for evaluation of dioxin toxicity in this study. The aim of the research is to develop a real time sensing system by using a micro instrument with novel function, which combines the biological field and micro instrumentation, for the analysis of Dioxins generated at the air flue. The micro instrument was made of Si and glass by photolithograph fabrication. We established prototype model for the system. Micro beads coated with Avidine were used as a reaction medium. Reaction chamber was filled with the micro beads and then the receptor immunoassay was carried out in the micro chamber. Poly-aromatic hydrocarbon with highly flat structure was used as a test sample. The reactivity was evaluated with fluorometry. The fluorescence was detected by fluorescent microscopy.
一般社団法人日本機械学会の論文
2004-03-03