1526 はっ水性壁面が生体流体のマイクロ流れに及ぼす影響

概要

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Bio-fluids flow in Bio-MEMS (Bio-Micro-Electrical-Mechanical-Systems) or μTAS (Micro-Total-Analytical-Systems) chips, which are recently attracted, have some problems such as deformation of bio-molecules and aggregation of bio-molecules to a wall. Such problems can cause blockage or breakage of the chips. In this work, we aim to evaluate biofluids flow on a hydrophobic surface for preventing aggregation of bio-molecules. Concretely, relation between pressure drop and volumetric flowrate was investigated. While flow in the hydrophilic micro-tubes with 100μm order for diameter agreed well with the conventional Hagen-Poiseuille equation, results for hydrophobic micro-tubes show that volumetric flowrates was larger than analytical value of those. For biofluid flow, the aggregation of bio-molecules could lessen the effects of increasing volumetric flowrates. The evaluations of aggregation on the hydrophobic surface for biofluid are now on investigating.
一般社団法人日本機械学会の論文
2003-08-05