免疫不全マウスにおける肝吸虫寄生の経過ならびに病理変化

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概要

• 論文の詳細を見る

• 免疫的に不全なSCIDおよびヌードマウスと免疫的に正常なFVB/NJとBALB/cA系統マウスを用いて,肝吸虫 Clonorchis sinensis のメタセルカリアを投与した寄生経過と組織病理変化について,比較を行った.その結果,肝吸虫の寄生経過は,各系統のマウスの肝における寄生防御機構,すなわち炎症性細胞浸潤,虫嚢形成,線維症などの一連の病理変化と深い関わりを有することが示された.また,FVB/NJマウスはヒト肝吸虫症を理解する上で重要なモデルになることが示唆された

• 社団法人日本獣医学会の論文
• 2001-04-25

著者

• HYUN Byung-Hwa

  ICLAS Monitoring Subcenter Korea, Korea Research Institute of Bioscience and Biotechnology

• CHOI Yang-Kyu

  College of Veterinary Medicine, Konkuk University

• Kim Doo-young

  School Of Electrical Eng. Seoul National Univ.

• Kim D‐y

  Seoul National Univ. And School Of Agricultural Biotechnol. Suwon Kor

• Yoon B‐i

  Division Of Cell And Molecular Pathogenesis Department Of Pathology Virginia Commonwealth University

• Yoon Byung-il

  Virginia Commonwealth University

• Yoon Byung-h

  Departments Of Veterinary Pathology Seoul National University

• Kim Dae-yong

  Department Of Veterinary Pathology College Of Veterinary Medicine And Agricultural Biotechnology Seo

• Kim Dae-yong

  Departments Of Veterinary Pathology Seoul National University

• Kim Dae-yong

  ソウル大学校獣医農学生命科学部病理学教室

• Kim Dae-yong

  ソウル大学獣医学部獣医病理学教室

• Choi Yang-kyu

  Genetic Resources Center Korea Research Institute Of Bioscience And Biotechnology (kribb)

• YOON Byung-II

  ソウル大学獣医学部獣医病理学教室

• CHOI Yang-Kyu

  韓国生命科学研究所

• HYUN Byung-Hwa

  韓国生命科学研究所

• JOG Kyoung-Hwan

  コリア大学医学部寄生虫学教室

• RIM Han-Jong

  コリア大学医学部寄生虫学教室

• LEE Jae-Hyun

  韓国ガンセンター実験病理学教室

• Hyun B‐h

  Korea Res. Inst. Biosci. And Biotechnol.(kribb) Taejon Kor

• Hyun Byung-hwa

  Genetic Resources Center Korea Research Institute Of Bioscience And Biotechnology (kribb)

• Kim D‐y

  Department Of Veterinary Pathology College Of Veterinary Medicine Seoul National University And Scho

• Yoon Byung-il

  Division Of Cell And Molecular Pathogenesis Department Of Pathology Virginia Commonwealth University

• Yoon Byung-Il

  ソウル大学獣医学部獣医病理学教室

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