Preparation of Axially Chiral Biphenyl Diphosphine Ligands and Their Application in Asymmetric Hydrogenation
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概要
- 論文の詳細を見る
Axially chiral biphenyldiphosphine ligands bearing diphenylphosphino group (s) and/or dicyclohexylphosphino group (s) were prepared in enantiomerically pure form starting from 2, 6-dimethylnitrobenzene via 8 steps : iodination, reduction, methoxylation through diazotization, Ullmann coupling, bromination, phosphorylation, optical resolution, and silane reduction, and the obtained ligands were used in rhodium-catalyzed asymmetric hydrogenation.
- 公益社団法人日本薬学会の論文
- 2004-12-01
著者
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YAMAMOTO Naoko
School of Humanities and Social Sciences at Osaka Prefecture University
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Yoshikawa Kiyoshi
Institute Of Atomic Energy Kyoto University
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Yoshikawa Kiyoshi
School Of Pharmaceutical Sciences University Of Shizuoka
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Achiwa Kazuo
School Of Pharmaceutical Sciences University Of Shizuoka
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Morimoto Toshiaki
School Of Pharmaceutical Sciences University Of Shizuoka
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Yoshikawa K
School Of Pharmaceutical Sciences University Of Shizuoka
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MURATA Masanao
School of Pharmaceutical Sciences, University of Shizuoka
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Yamamoto Naoko
School Of Pharmaceutical Sciences University Of Shizuoka
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Murata Masanao
School Of Pharmaceutical Sciences University Of Shizuoka
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