ラクタム類の研究(第16報)X線結晶解析による1-Benzyl-5-ethyl-1,2,5,6-tetrahydro-2-oxo-4-pyridineacetic Acidの分子構造
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概要
- 論文の詳細を見る
X-Ray analysis of a single crystal of 1-benzyl-5-ethyl-1,2,5,6-tetrahydro-2-oxo-4-pyridineacetic acid (1) has confirmed the location of the C=C bond, planarity of the α, β-unsaturated δ-valerolactam ring, and an axial-like conformation of the ethyl group at the 5-position, which were recently proposed on the basis of chemical and spectroscopic evidence. The carboxylic hydroxyl group and the lactam carbonyl group in the molecule examined respectively form hydrogen bonds with the lactam carbonyl and the carboxyl group of another molecule, producing a cyclic dimer.
- 公益社団法人日本薬学会の論文
- 1979-08-25
著者
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青江 啓一
田辺製薬株式会社有機化学研究所
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藤井 澄三
金沢大学薬学部
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Ohba M
Faculty Of Pharmaceutical Sciences Kanazawa University
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伊達 忠正
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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青江 啓一
Organic Chemistry Research Laboratory:tanabe Seiyaku Co. Ltd.
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