Hypogycemic and Aldose Reductase Activity of Polichia campestris
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概要
- 論文の詳細を見る
The hypoglycemic activity of 80% methanol extract of Polichia campestris (PM) was investigated in both normal and streptozotocin-induced diabetic mice, one of the insulin-dependent diabetic mellitus. PM (300 mg/kg) reduced the blood glucose of normal mice from 2 to 7 h after oral administration. It also decreased hyperglycemia from 594±46 to 472±31 mg/dl 4 h after oral administration in streptozotocin-induced diabetic mice (p<0.05). PM strongly increased glucose uptake in adipose tissues. In addition, the petroleum ether fraction of PM inhibited aldose reductase activity. These experimental results suggest that the antidiabetic activity of Polichia campestris supports its use in traditional medicine.
- 公益社団法人日本薬学会の論文
- 1996-06-15
著者
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MIURA Toshihiro
Suzuka University of Medical Science
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KATO Atsushi
Kobe Pharmaceutical University
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Kato Atsushi
Department Of Hospital Pharmacy Graduate School Of Medicine And Pharmaceutical Sciences University O
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Miura Toshihiro
Suzuka University Of Medical Science And Technology
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