Isolation of an Escherichia coli Mutant Which Permits the High-Level Expression of a Streptomycin-Resistance Gene Derived from Pseudomonas aeruginosa
スポンサーリンク
概要
- 論文の詳細を見る
Pretreatment with streptomycin at a low concentration influenced the susceptibility to streptomycin of a strain of Escherichia coli carrying a streptomycin-resistance plasmid, pSA1700,derived from Pseudomonas aeruginosa. This phenomenon was due to a mutation that occurred at about 10^<-8>-10^<-10> of frequency in a regulatory gene involved in gene expression on the chromosome of E. coli. A product encoded by the regulatory gene on the chromosome of E. coli might normally repress gene expression by binding to part of the promoter region of the streptomycin-resistance gene derived from P. aeruginosa.
- 公益社団法人日本薬学会の論文
- 1998-03-15
著者
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SASATSU Masanori
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
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HAMASHIMA Hajime
Department of Microbiology, Showa Pharmaceutical University
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Sasatsu M
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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Sasatsu Masanori
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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KAZAMA HITOSHI
Department of Microbiology, Showa College of Pharmaceutical Sciences
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ARAI TAKETOSHI
Department of Microbiology, Showa College of Pharmaceutical Sciences
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Arai Taketoshi
Department Of Microbiology Showa College Of Pharmaceutical Science
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Arai Taketoshi
Department Of High Temperature Engineering Japan Atomic Energy Research Institute
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Kazama Hitoshi
Department Of Microbiology Showa College Of Pharmaceutical Sciences
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Kazama Hitoshi
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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Hamashima Hajime
Department Of Microbiology Showa Phamaceutical University
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Hamashima Hajime
Department Of Microbiology Showa College Of Pharmacy
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Sasatsu Masanori
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
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