The Antibacterial Effects of Myrcene on Staphylococcus aureus and Its Role in the Essential Oil of the Tea Tree (Melaleuca alternifolia)
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概要
- 論文の詳細を見る
To clarify the nature of the antibacterial activity of tea tree oil (TTO; an essential oil of Melaleuca alternifolia), we investigated the antibacterial effects of m yrcene on Staphylococcus aureus FDA209 and the effects of the combination of myrcene and terpinen-4-ol. The results were compared with that in the case of other components of TTO. Using S. aureus FDA209P as the test organism, we assessed antibacterial activity in terms of the growth inhibition and the leakage of K^+ ions from bacterial cells. Myrcene suppressed the growth of S. aureus, as did TTO, and the effect was dependent on damage to cell membranes. A mixture of myrcene and terpinen-4-ol had activity similar to that of TTO with respect to leakage of K^+ ions from S. aureus. Myrcene acts as an antibacterial agent against S. aureus and is an important contributor to the antibacterial activity of TTO.
- 日本生薬学会の論文
- 2004-02-20
著者
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SHIRAISHI Akiko
Department of Microbiology, Showa Phamaceutical University
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Shimada Jingoro
Showa Pharmaceutical Univ. Tokuo Jpn
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Shimada Jingoro
Department Of Microbiology And Medicine Division Of Clinical Pharmacology Institute Of Medical Scien
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Hamashima Hajime
Department Of Microbiology Showa Phamaceutical University
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Hamashima Hajime
Department Of Microbiology Showa College Of Pharmacy
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Shiraishi A
Department Of Microbiology Showa Phamaceutical University
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Inoue Yoshihiro
Department Of Critical Care Medicine Iwate Medical University
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Shimada Jingoro
Department Of Microbiology Showa Pharmaceutical University
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Hada Toshiko
Department of Microbiology, Showa Pharmaceutical University
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Hada Toshiko
Department Of Microbiology Showa Pharmaceutical University
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Shiraishi Akiko
Department Of Microbiology Showa Phamaceutical University
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SHIMADA Jingoro
Department of Internal Medicine, Jikei University School of Medicine
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INOUE YOSHIHIRO
Department of Anatomy, Okayama University School of Dentistry
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