Frequency and Genetic Characterization of Multidrug-Resistant Mutants of Staphylococcus aureus after Selection with Individual Antiseptics and Fluoroquinolones
スポンサーリンク
概要
- 論文の詳細を見る
The frequency of generation of multidrug-resistant mutants of Staphylococcus aureus was examined by selection with various antiseptics and fluoroquinolones and the mutated genes were characterized. Multidrug-resistant mutants with mutation of the region between the promoter and structural regions of the norA gene were generated more frequently during selective pressure with antiseptics than during selective pressure with EQs. We also obtained evidence for the existence of at least one other gene related to resistance to antiseptics and fluoroquinolones on the chromosome of S. aureus in addition to norA gene.
- 公益社団法人日本薬学会の論文
- 2002-09-01
著者
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NOGUCHI Norihisa
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
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Narui Koji
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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SASATSU Masanori
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
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Noguchi Norihisa
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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Noguchi Norihisa
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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Noguchi Norihisa
Tokyo University Of Pharmacy And Life Science
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Sasatsu M
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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Sasatsu Masanori
Department Of Microbiology School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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WAKASUGI Kazunori
Division of Clinical Immunohaematology, Department of Internal Medicine, Tokyo Medical University at
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TAMURA Maki
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
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Tamura M
Osaka Univ. Medical School Osaka Jpn
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Wakasugi Kazunori
Division Of Clinical Immunohaematology Department Of Internal Medicine Tokyo Medical University At H
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Sasatsu Masanori
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
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