Heteroaromatic Analogs of Benzomorphan. III. Synthesis of 1,2,3,4,5,6-Hexahydro-2,6-methano-3-methylpyrido [3,2-d] azocine
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概要
- 論文の詳細を見る
6-Acetamido-5,6,7,8-tetrahydroquinoline N-oxide (VI) was derived to the 8-oxo derivative (IX) via the acetoxy compound (VII). Introduction of carboxymethyl group by a Witting reaction of IX and catalytic hydrogenation afforded the amido ester (XI). The title compound (XVI) was synthesized from the amino acid ester (XII) by intramolecular cyclization and the subsequent lithium aluminum hydride reduction of the resulting lactam.
- 公益社団法人日本薬学会の論文
- 1976-11-25
著者
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野村 敬一
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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安立 準
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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三橋 監物
Faculty of Pharmaceutical Sciences, University of Toyama
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山本 真一
Faculty of Pharmaceutical Sciences, University of Toyama
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三橋 監物
Faculty Of Pharmaceutical Sciences Josai University
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山本 真一
Faculty Of Pharmaceutical Sciences University Of Toyama
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