Heteroaromatic Analogs of Benzomorphan. Synthesis of Novel Thiazolo [4,5-f] morphans

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Monothiazolization of ethyl 2-methyl-1,3-dioxo-2-cyclohexaneacetate (I) afforded 2-aminothiazole derivative (IIa) corresponding to tetralone. In several steps, IIa was converted to some thiazolo [4,5-f] morphans (X) via 9-oxothiazolo [4,5-f] morphan (VIII).
公益社団法人日本薬学会の論文
1981-06-25

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