Thermodynamic Properties of Polymorphs of Tolbutamide
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概要
- 論文の詳細を見る
Thermodynamic values for two polymorphic forms of tolbutamide (form A and form B) were calculated on the basis of solubility determination and differential scanning calorimetry. The transition temperature and the heat of transition were estimated to be 93.3℃, and 230 cal/mol by the former method, and 98.5℃, and 255 cal/mol by the latter method. The dissolution rate was only slightly affected by the polymorphic form.
- 公益社団法人日本薬学会の論文
- 1982-07-25
著者
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上田 晴久
星薬科大学
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南部 直樹
Faculty Of Pharmaceutical Sciences Hoshi University
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永井 恒司
Hoshi Institute of Pharmaceutical Sciences
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南部 直樹
Hoshi Institute of Pharmaceutical Sciences
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上田 晴久
Hoshi Institute of Pharmaceutical Sciences
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