Neurotropic and Psychotropic Agents. VII. Synthesis and Pharmacological Properties of 2-(Alkoxyalkylamino)-3H-1,4-benzodiazepines
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概要
- 論文の詳細を見る
The synthesis and pharmacological properties of some 2-(alkoxyalkylamino)-3H-1,4-benzodiazepine derivatives (I and II) are described. Compounds I were prepared from the corresponding 2-methylthio-1,4-benzodiazepines and primary amines. Compounds II were prepared by alkylation of the corresponding 2-monoalkylamino-1,4-benzodiazepines with alkyl or alkoxyalkyl halides. The compounds (I and II) showed tranquilizing profiles like that of chlordiazepoxide in taming and anticonvulsant tests in mice.
- 社団法人日本薬学会の論文
- 1982-04-25
著者
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松尾 昌昭
New Drug Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.,
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植田 育男
Institute Of Scientific And Industrial Reseach Osaka University
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植田 育男
Central Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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谷口 清
New Drug Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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松尾 昌昭
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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谷口 清
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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松尾 昌昭
New Drug Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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