Total Synthesis of Pyrrolnitrin. VII. Synthesis of 2,5-Dimethyl-3-arylpyrrole
スポンサーリンク
概要
- 論文の詳細を見る
Preparation of 2,5-dimethyl-3-arylpyrrole (IX) was accomplished by three different routes : at first alkyl 3-aryl-5-methyl-4-pyrrolecarboxylate (IV) was converted to IX by the series of reactions containing Mannich reaction, reduction and decarboxylation, and secondly IX was also prepared by the ringclosure of 3-aryl-2,5-hexanedione (XIV) with ammonium acetate and thirdly the methiodide of a bis-Mannich base (XVIII) prepared by Mannich reaction of 3-arylpyrrole (XVII) was reduced with sodium borohydride to IX.
- 社団法人日本薬学会の論文
- 1969-03-25
著者
-
海尾 澄則
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
刈米 和夫
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
田中 邦彦
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
植田 育男
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
田中 邦彦
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
刈米 和夫
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
植田 育男
Central Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
海尾 澄則
Fujisawa Pharmaceutical Co. Ltd.
関連論文
- Total Synthesis of Pyrrolnitrin. II. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (1)
- Pyrrolnitrinの全合成
- 1.Pyrrolnitrinの全合成並びにその類似化合物の合成
- Total Synthesis of Pyrrolnitrin. V. Synthesis of Pyrrolnitrin and Its Analogues. (1)
- New 2-Aryliminoimidazolidines. I. Synthesis and Antihypertensive Properties of 2-(2-Phenoxyphenylimino) imidazolidines and Related Compounds
- Neurotropic and Psychotropic Agents. VII. Synthesis and Pharmacological Properties of 2-(Alkoxyalkylamino)-3H-1,4-benzodiazepines
- Neurotropic and Psychotropic Agents. V. An Improved Synthesis of 7-Chloro-5-(2-chlorophenyl)-2-(2-dimethylaminoethylthio)-3H-1,4-benzodiazepine and Related Compounds
- Neurotropic and Psychotropic Agents. IV. Synthesis and Pharmacological Properties of 7-Chloro-5-(2-chlorophenyl)-2-(2-dimethylaminoethylthio)-3H-1,4-benzodiazepine and Related Compounds
- The Structures of Tomaymycin and Oxotomaymycin
- Studies on Insecticides. VI. Synthesis of Proline Derivatives.
- Studies on Insecticides. V. Synthesis of 2-Piperidone Derivatives.
- Neurotropic and Psychotropic Agents. VI. 1-Alkoxymethyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones
- Synthesis and Pharmacological Properties of 8-Chloro-10-(2-dimethylaminoethoxy) dibenzo [b, f] thiepin and Related Compounds. Neurotropic and Psychotropic Agents. III
- The Synthesis of 10-(4-Methylpiperazino) dibenzo [b, f] thiepin and Related Compounds. Neurotropic and Psychotropic Agents
- Structure-Activity Studies of Pyrrolnitrin Analogues
- Total Synthesis of Pyrrolnitrin. X. Synthesis of Pyrrolnitrin. (2)
- Total Synthesis of Pyrrolnitrin. IX. Synthesis of Dialkyl 3-Aryl-2,5-pyrroledicarboxylates and Alkyl β-Aryl-5-methyl-2-pyrrolecarboxylates
- Total Synthesis of Pyrrolnitrin. VIII. A New Method of Pyrrole Ringclosure using Aminoacetal
- Total Synthesis of Pyrrolnitrin. VII. Synthesis of 2,5-Dimethyl-3-arylpyrrole
- Total Synthesis of Pyrrolnitrin. VI. Synthesis of Nitro-chloro-2-aminoacetophenones and 1-Aryl-1,3-butanediones
- Total Synthesis of Pyrrolnitrin. IV. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (3)
- Total Synthesis of Pyrrolnitrin. III. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (2)
- Total Synthesis of Pyrrolnitrin. I. Synthesis of 3-Arylpyrrole Derivatives by Knorr's Condensation
- 4 Pyrrolnitrinの全合成
- Synthesis of DL-Thiamic Acid
- Studies on the Synthesis of 17β-Hydroxyandrostan-3-one