Total Synthesis of Pyrrolnitrin. IV. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (3)
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概要
- 論文の詳細を見る
Treatment of the crude-enamine (IV), prepared from 1-(3-chlorophenyl)-1,3-butanedione (II) and diethyl aminomalonate (III), with sodium ethoxide gave ethyl 3-(3-chlorophenyl)-5-methyl-2-pyrrolecarboxylate (VI) and ethyl 2-(3-chlorophenyl)-4-methyl-5-pyrrolecarboxylate (VII'), whose structures were confirmed by other synthetic methods. Mechanism of above reaction and ultraviolet absorption spectra of these pyrrole derivatives were discussed.
- 社団法人日本薬学会の論文
- 1969-03-25
著者
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海尾 澄則
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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刈米 和夫
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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田中 邦彦
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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野口 英世
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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野口 英世
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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野口 英世
藤沢薬品工業株式会社中央研究所
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田中 邦彦
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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刈米 和夫
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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海尾 澄則
Fujisawa Pharmaceutical Co. Ltd.
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