Utility of the Substituent Entropy Constants σ_s^o in the Studies of Quantitative Structure-Activity Relationships
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概要
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Values of the substituent entropy constants σ_s^o for monosubstituted methane and benzene derivatives were determined from the standard entropy of the 3rd law of thermodynamics. This parameter is orthogonal to σ_t or σ_π, and seems preferable to π, E_s, MR, M_w, P_r and V_w. Two examples of QSAR are successfully analysed in terms of σ_s^o.
- 公益社団法人日本薬学会の論文
- 1981-10-25
著者
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川木 秀子
Faculty of Pharmaceutical Sciences, Kinki University
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佐々木 喜男
Faculty of Pharmaceutical Sciences, Osaka University
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佐々木 喜男
Faculty Of Pharmaceutical Sciences Osaka University
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高木 達也
Faculty of Pharmaceutical Sciences, Osaka University
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岩田 昭裕
Faculty of Pharmaceutical Sciences, Osaka University
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川木 秀子
Faculty Of Pharmaceutical Sciences Kinki University
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岩田 昭裕
Faculty Of Pharmaceutical Sciences Osaka University
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山里 洋吉
Faculty of Pharmaceutical Sciences, Osaka University
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岩田 喜裕
Faculty of Pharmaceutical Sciences, Osaka University
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山里 洋吉
Faculty Of Pharmaceutical Sciences Osaka University
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